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Gene Expression Data
Assay Details
Assay
Reference: J:272623 Kinoshita-Kawada M, et al., A crucial role for Arf6 in the response of commissural axons to Slit. Development. 2019 Feb 4;146(3):dev172106
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6390948
Gene symbol: Cntn2
Gene name: contactin 2
Antibody: anti-TAG-1 (4D7)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 5A Wild-type: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 5A WT TAG-1 top , 5A WT TAG-1 bottom , 5A WT TAG-1/DIC Expression is in commissural axons that extend ventrally in the medial part of the the ventral funiculus.
Specimen 5A Arf6+/-: embryonic day 12.5; Arf6tm1Yaka/Arf6+ (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 5A Arf6+/- TAG-1/DIC , 5A Arf6+/- TAG-1 top , 5A Arf6+/- TAG-1 bottom Expression is in commissural axons that extend ventrally in the medial part of the the ventral funiculus.
Specimen 5A Arf6-/-: embryonic day 12.5; Arf6tm1Yaka/Arf6tm1Yaka (more )
Structure Level Pattern Image Note
TS20: spinal cord Weak Regionally restricted 5A Arf6-/- TAG-1/DIC , 5A Arf6-/- TAG-1 top , 5A Arf6-/- TAG-1 bottom Expression is in commissural axons that extended ventrally, similar to wild-type embryos but in this mutant immunoreactivity was reduced in the medial ventral funiculus to only 32.3% of the wild-type levels.
Specimen S7A E11.0: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: future spinal cord Present Regionally restricted S7A E11.0 bottom , S7A E11.0 top Expression is in the medial part of the the ventral funiculus at brachial-level spinal cords.
Specimen S7A E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted S7A E11.5 top , S7A E11.5 bottom Expression is in the medial part of the the ventral funiculus at brachial-level spinal cords.
Specimen S7A E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted S7A E12.5 top , S7A E12.5 bottom Expression is in the medial part of the the ventral funiculus at brachial-level spinal cords.
Specimen S7B Wild-type: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted S7B WT Expression is in commissural axons that extend ventrally in the medial part of the the ventral funiculus.
Specimen S7B Arf6+/-: embryonic day 12.5; Arf6tm1Yaka/Arf6+ (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted S7B Arf6+/- Expression is in commissural axons that extend ventrally in the medial part of the the ventral funiculus.
Specimen S7B Arf6-/-: embryonic day 12.5; Arf6tm1Yaka/Arf6tm1Yaka (more )
Structure Level Pattern Image Note
TS20: spinal cord Weak Regionally restricted S7B Arf6-/- Expression is in commissural axons that extended ventrally, similar to wild-type embryos but in this mutant immunoreactivity was reduced in the medial ventral funiculus to only 32.3% of the wild-type levels.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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