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Tg(KRT14-Igf1_iM)CNros
Transgene Detail
Summary
Symbol: Tg(KRT14-Igf1_iM)CNros
Name: transgene insertion C, Nadia Rosenthal
MGI ID: MGI:6390141
Synonyms: K14/mIGF-1
Transgene: Tg(KRT14-Igf1_iM)CNros  Location: unknown  
Alliance: Tg(KRT14-Igf1_iM)CNros page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe human promoter drives keratinocyte-specific expression of the rat cDNA for isoform M followed by a 700 bp beta-globin intron and 500 bp of the KRT14 polyadenylation sequence. Two lines were selected for further analysis with line C exhibiting C exhibiting higher expression than line F. (J:143435)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:143435 Semenova E, et al., Overexpression of mIGF-1 in keratinocytes improves wound healing and accelerates hair follicle formation and cycling in mice. Am J Pathol. 2008 Nov;173(5):1295-310
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory