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Gene Expression Data
Assay Details
Assay
Reference: J:267245 Manuylov NL, et al., Cardiac expression of Tnnt1 requires the GATA4-FOG2 transcription complex. ScientificWorldJournal. 2009 Jul 4;9:575-87
Assay type: RNA in situ
MGI Accession ID: MGI:6389800
Gene symbol: Tnnt1
Gene name: troponin T1, skeletal, slow
Probe: Tnnt1 probe1
Probe preparation: labelled with digoxigenin
Results
Specimen 1A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: outflow tract Present 1A

Specimen 1B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart Present Regionally restricted 1B Expression in forming interventricular groove.

Specimen 1C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart Present Regionally restricted 1C Expression expands posteriorly towards the apex.
TS17: primitive ventricle Present Regionally restricted 1C Expression appears in left ventricle.

Specimen 1D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart Present Regionally restricted 1D Expression expands posteriorly towards the apex.
TS17: primitive ventricle Present Regionally restricted 1D Expression appears in left ventricle.

Specimen 1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: primitive ventricle Present Regionally restricted 1E Expression appears in left ventricle.

Specimen E11.5 not shwon: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: outflow tract Weak Expression down-regulated in outflow tract.

Specimen 1F: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: interventricular groove Present 1F Expression mostly confined to ventral interventricular groove.
TS20: heart left ventricle Present 1F Some expression in left ventricle.
TS20: outflow tract Absent 1F

Specimen 1G: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: heart Present Regionally restricted 1G Interventricular expression expands laterally.

Specimen 1H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: heart left ventricle Present Regionally restricted 1H Expression throughout ventral side of left ventricle.
TS22: heart right ventricle Present Regionally restricted 1H Expression in right ventricle enhanced in apical region.
TS22: outflow tract Absent 1H

Specimen 2B Ventral view: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: left atrium Strong 2B Ventral view Atrium expression becomes more prominent. Left atrium more positive for expression.
TS20: interventricular groove Present 2B Ventral view

Specimen 2B Dorsal view: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: left atrium Strong 2B Dorsal view Atrium expression becomes more prominent. Left atrium more positive for expression.
TS20: interventricular groove Present 2B Dorsal view

Specimen 2C Ventral view: embryonic day 12.5; Zfpm2tm1Sho/Zfpm2tm1Sho (more )
Structure Level Pattern Image Note
TS20: outflow tract Weak 2C Ventral view Expression downregulated, resembling the E9.5 wild-type pattern. Expression persisting in outflow tract and apical portion of interventricular groove.
TS20: interventricular groove Weak Regionally restricted 2C Ventral view Expression downregulated, resembling the E9.5 wild-type pattern. Expression persisting in outflow tract and apical portion of interventricular groove.

Specimen 2C Dorsal view: embryonic day 12.5; Zfpm2tm1Sho/Zfpm2tm1Sho (more )
Structure Level Pattern Image Note
TS20: outflow tract Weak 2C Dorsal view Expression downregulated, resembling the E9.5 wild-type pattern. Expression persisting in outflow tract and apical portion of interventricular groove.
TS20: interventricular groove Weak Regionally restricted 2C Dorsal view Expression downregulated, resembling the E9.5 wild-type pattern. Expression persisting in outflow tract and apical portion of interventricular groove.

Specimen Foxg2 null not shown: embryonic day 12.5; Zfpm2tm1Sho/Zfpm2tm1Sho (more )
Structure Level Pattern Image Note
TS20: skeletal muscle Present

Specimen 2D Ventral view: embryonic day 12.5; Gata4tm1Sho/Gata4tm1Sho (more )
Structure Level Pattern Image Note
TS20: heart atrium Absent 2D Ventral view
TS20: heart ventricle Absent 2D Ventral view

Specimen 2D Dorsal view: embryonic day 12.5; Gata4tm1Sho/Gata4tm1Sho (more )
Structure Level Pattern Image Note
TS20: heart atrium Absent 2D Dorsal view
TS20: heart ventricle Absent 2D Dorsal view

Specimen Gata4 ki/ki not shown: embryonic day 12.5; Gata4tm1Sho/Gata4tm1Sho (more )
Structure Level Pattern Image Note
TS20: skeletal muscle Present

Specimen 3A Ventral view: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: heart Weak 3A Ventral view

Specimen 3A Dorsal view: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: heart Weak 3A Dorsal view


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory