Gene Expression Data
Assay Details
Assay
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Reference:
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J:280430
Janeckova E, et al., Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019;14(10):e0223879
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6388610
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Gene symbol:
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Gli1
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Gene name:
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GLI-Kruppel family member GLI1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
2A:
embryonic day 14.5; Gli1tm2Alj/Gli1 +
(more )
Specimen
2A:
(close )
Genetic Background:
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involves: 129S6/SvEvTac
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Mutant Allele(s):
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Gli1tm2Alj/Gli1+
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Age:
|
embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: tensor veli palatini |
Present |
Non-Uniform |
2A
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Expression was plentiful in the cranial neural crest-derived mesenchymal cells surrounding myogenic cells.
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Specimen
2B:
embryonic day 14.5; Gli1tm2Alj/Gli1 +
(more )
Specimen
2B:
(close )
Genetic Background:
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involves: 129S6/SvEvTac
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Mutant Allele(s):
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Gli1tm2Alj/Gli1+
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Age:
|
embryonic day 14.5
|
Sex:
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Not Specified
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Type:
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section
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Fixation:
|
10% Formalin
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Embedding:
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Cryosection
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Specimen
2C:
embryonic day 14.5; Gli1tm2Alj/Gli1 +
(more )
Specimen
2C:
(close )
Genetic Background:
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involves: 129S6/SvEvTac
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Mutant Allele(s):
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Gli1tm2Alj/Gli1+
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Age:
|
embryonic day 14.5
|
Sex:
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Not Specified
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Type:
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section
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Fixation:
|
10% Formalin
|
Embedding:
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Cryosection
|
Specimen
2D:
embryonic day 14.5; Gli1tm2Alj/Gli1 +
(more )
Specimen
2D:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac
|
Mutant Allele(s):
|
Gli1tm2Alj/Gli1+
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
|
10% Formalin
|
Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: soft palate |
Present |
Regionally restricted |
2D
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In the putative region of the palatopharyngeus, abundant expression was present in the cranial neural crest-derived mesenchymal cells.
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TS22: palatal shelf epithelium |
Present |
|
2D
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Specimen
2E:
embryonic day 16.5; Gli1tm2Alj/Gli1 +
(more )
Specimen
2E:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac
|
Mutant Allele(s):
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Gli1tm2Alj/Gli1+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
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Type:
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section
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Fixation:
|
10% Formalin
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: soft palate |
Present |
|
2E
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At E16.5, overall fewer Gli1-positive cells were observed in the soft palatal region.
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TS24: tensor veli palatini |
Present |
Non-Uniform |
2E
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The majority of the Gli1-positive cells persisted in the cranial neural crest-derived mesenchyme both surrounding the myogenic fibers and adjacent to the epithelium.
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Specimen
2F:
embryonic day 16.5; Gli1tm2Alj/Gli1 +
(more )
Specimen
2F:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac
|
Mutant Allele(s):
|
Gli1tm2Alj/Gli1+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: soft palate |
Present |
|
2F
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At E16.5, overall fewer Gli1-positive cells were observed in the soft palatal region.
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TS24: palatoglossus |
Present |
Non-Uniform |
2F
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The majority of the Gli1-positive cells persisted in the cranial neural crest-derived mesenchyme both surrounding the myogenic fibers and adjacent to the epithelium.
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TS24: soft palate epithelium |
Present |
|
2F
|
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Specimen
2G:
embryonic day 16.5; Gli1tm2Alj/Gli1 +
(more )
Specimen
2G:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac
|
Mutant Allele(s):
|
Gli1tm2Alj/Gli1+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
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section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: soft palate |
Present |
|
2G
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At E16.5, overall fewer Gli1-positive cells were observed in the soft palatal region.
|
TS24: palatoglossus |
Present |
Non-Uniform |
2G
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The majority of the Gli1-positive cells persisted in the cranial neural crest-derived mesenchyme both surrounding the myogenic fibers and adjacent to the epithelium.
|
TS24: soft palate epithelium |
Present |
|
2G
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Specimen
2H:
embryonic day 16.5; Gli1tm2Alj/Gli1 +
(more )
Specimen
2H:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac
|
Mutant Allele(s):
|
Gli1tm2Alj/Gli1+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: soft palate |
Present |
Non-Uniform |
2H
|
At E16.5, overall fewer Gli1-positive cells were observed in the soft palatal region. The majority of the Gli1-positive cells persisted in the cranial neural crest-derived mesenchyme both surrounding the myogenic fibers and adjacent to the epithelium.
|
TS24: soft palate epithelium |
Present |
|
2H
|
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Specimen
2I:
embryonic day 18.5; Gli1tm2Alj/Gli1 +
(more )
Specimen
2I:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac
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Mutant Allele(s):
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Gli1tm2Alj/Gli1+
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Age:
|
embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: tensor veli palatini |
Weak |
Single cells |
2I
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At E18.5, overall expression remained low, except a few positive cells were detected in the cranial neural crest-derived mesenchyme.
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Specimen
2J:
embryonic day 18.5; Gli1tm2Alj/Gli1 +
(more )
Specimen
2J:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac
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Mutant Allele(s):
|
Gli1tm2Alj/Gli1+
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Age:
|
embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Cryosection
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Specimen
2K:
embryonic day 18.5; Gli1tm2Alj/Gli1 +
(more )
Specimen
2K:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac
|
Mutant Allele(s):
|
Gli1tm2Alj/Gli1+
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
10% Formalin
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Embedding:
|
Cryosection
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Specimen
2L:
embryonic day 18.5; Gli1tm2Alj/Gli1 +
(more )
Specimen
2L:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac
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Mutant Allele(s):
|
Gli1tm2Alj/Gli1+
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
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Type:
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section
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Fixation:
|
10% Formalin
|
Embedding:
|
Cryosection
|
|