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Gene Expression Data
Assay Details
Assay
Reference: J:280430 Janeckova E, et al., Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019;14(10):e0223879
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6388610
Gene symbol: Gli1
Gene name: GLI-Kruppel family member GLI1
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 14.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS22: tensor veli palatini Present Non-Uniform 2A Expression was plentiful in the cranial neural crest-derived mesenchymal cells surrounding myogenic cells.

Specimen 2B: embryonic day 14.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS22: palatoglossus Present Non-Uniform 2B Expression was abundant in the cranial neural crest-derived mesenchymal cells.
TS22: palatal shelf epithelium Present 2B

Specimen 2C: embryonic day 14.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS22: levator veli palatini Present Non-Uniform 2C Expression was abundant in the cranial neural crest-derived mesenchymal cells surrounding myogenic fibers close to the epithelium.
TS22: palatal shelf epithelium Present 2C

Specimen 2D: embryonic day 14.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS22: soft palate Present Regionally restricted 2D In the putative region of the palatopharyngeus, abundant expression was present in the cranial neural crest-derived mesenchymal cells.
TS22: palatal shelf epithelium Present 2D

Specimen 2E: embryonic day 16.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS24: soft palate Present 2E At E16.5, overall fewer Gli1-positive cells were observed in the soft palatal region.
TS24: tensor veli palatini Present Non-Uniform 2E The majority of the Gli1-positive cells persisted in the cranial neural crest-derived mesenchyme both surrounding the myogenic fibers and adjacent to the epithelium.

Specimen 2F: embryonic day 16.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS24: soft palate Present 2F At E16.5, overall fewer Gli1-positive cells were observed in the soft palatal region.
TS24: palatoglossus Present Non-Uniform 2F The majority of the Gli1-positive cells persisted in the cranial neural crest-derived mesenchyme both surrounding the myogenic fibers and adjacent to the epithelium.
TS24: soft palate epithelium Present 2F

Specimen 2G: embryonic day 16.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS24: soft palate Present 2G At E16.5, overall fewer Gli1-positive cells were observed in the soft palatal region.
TS24: palatoglossus Present Non-Uniform 2G The majority of the Gli1-positive cells persisted in the cranial neural crest-derived mesenchyme both surrounding the myogenic fibers and adjacent to the epithelium.
TS24: soft palate epithelium Present 2G

Specimen 2H: embryonic day 16.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS24: soft palate Present Non-Uniform 2H At E16.5, overall fewer Gli1-positive cells were observed in the soft palatal region. The majority of the Gli1-positive cells persisted in the cranial neural crest-derived mesenchyme both surrounding the myogenic fibers and adjacent to the epithelium.
TS24: soft palate epithelium Present 2H

Specimen 2I: embryonic day 18.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS26: tensor veli palatini Weak Single cells 2I At E18.5, overall expression remained low, except a few positive cells were detected in the cranial neural crest-derived mesenchyme.

Specimen 2J: embryonic day 18.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS26: palatoglossus Weak Scattered 2J Scattered expression was detected in cranial neural crest-derived mesenchyme surrounding the muscle cells.
TS26: soft palate epithelium Present 2J

Specimen 2K: embryonic day 18.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS26: levator veli palatini Trace Single cells 2K The levator veli palatini was nearly absent of positive cells, with only few positive cells present in cranial neural crest-derived mesenchyme close to the epithelium.
TS26: soft palate epithelium Present 2K

Specimen 2L: embryonic day 18.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS26: soft palate Present Scattered 2L Scattered expression persisted in cranial neural crest-derived mesenchymal cells close to the epithelium.
TS26: soft palate epithelium Present 2L


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory