Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tnnt2em1(dre)Bzsh
Name:	troponin T2, cardiac; endonuclease-mediated mutation 1, Bin Zhou
MGI ID:	MGI:6386782
Synonyms:	Tnnt2-Dre
Gene:	Tnnt2  Location: Chr1:135764092-135779998 bp, + strand  Genetic Position: Chr1, 59.32 cM
Alliance:	Tnnt2em1(dre)Bzsh page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Tnnt2em1(dre)Bzsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tnnt2 (MGI:104597)   Mutation details: A cDNA encoding Dre recombinase was iserted into the site encoding the translational start codon of the Tnnt2 gene, using the CRISPR/Cas9 technology. (J:278073)

Activity:	Tissue activity of this recombinase allele
Driver:	Tnnt2 (mouse) Summary of all recombinase alleles driven by Tnnt2. Comparative matrix view of recombinase activities Alliance mouse Tnnt2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnnt2 Mutation:	52 strains or lines available

Original:	J:278073 He L, et al., Enhancing the precision of genetic lineage tracing using dual recombinases. Nat Med. 2017 Dec;23(12):1488-1498
All:	5 reference(s)