Tg(CAG-cas9,Rnu6-gRNA:Trp53,Krt14-a)E3BYtchn
Transgene Detail
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| Symbol: |
Tg(CAG-cas9,Rnu6-gRNA:Trp53,Krt14-a)E3BYtchn |
| Name: |
transgene insertion E3B, You-Tzung Chen |
| MGI ID: |
MGI:6386746 |
| Synonyms: |
CAGLSL-Cas9, ICE CRIM |
| Transgene: |
Tg(CAG-cas9,Rnu6-gRNA:Trp53,Krt14-a)E3BYtchn Location: unknown
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| Alliance: |
Tg(CAG-cas9,Rnu6-gRNA:Trp53,Krt14-a)E3BYtchn page
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| Transgene Type: |
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Transgenic (Endonuclease, Reporter) |
| Mutation: |
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Insertion
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Mutation details: Three transgenes were co-injected expressing cas9 under the conrol of the ubiquitous CAG promoter, Rnu6 promoter driving expression of a guide RNA targeting Trp52 and agouti allele under the control of the Krt14 promoter. The E3B line was generated.
(J:283235)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:283235 Fan HH, et al., P53 ICE CRIM mouse: a tool to generate mutant allelic series in somatic cells and germ lines for cancer studies. FASEB J. 2019 Apr;33(4):5571-5584 |
| All: |
1 reference(s) |
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Analysis Tools
