Tprg1ltm1.2Tdre
Targeted Allele Detail
|
|
| Symbol: |
Tprg1ltm1.2Tdre |
| Name: |
transformation related protein 63 regulated 1 like; targeted mutation 1.2, Thomas Dresbach |
| MGI ID: |
MGI:6385150 |
| Synonyms: |
Mover KO |
| Gene: |
Tprg1l Location: Chr4:154241942-154245123 bp, - strand Genetic Position: Chr4, 83.88 cM, cytoband E2
|
| Alliance: |
Tprg1ltm1.2Tdre page
|
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:282820
|
| Parent Cell Line: |
Not Specified (ES Cell)
|
| Strain of Origin: |
129P2/OlaHsd
|
|
| Allele Type: |
|
Targeted (Null/knockout) |
| Mutation: |
|
Intragenic deletion
|
| |
|
Mutation details: The targeting vector is designed to insert a loxP site in exon 1 (upstream of the translation start site), and an FRT-flanked neo cassette followed by a second loxP site downstream of exon 3. Flp-mediated recombination removed the FRT-flanked neo cassette. Cre-mediated recombination removed exons 1-3 and part of the downstream intron.
(J:282820)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Tprg1l Mutation: |
16 strains or lines available
|
|
| Original: |
J:282820 Akula AK, et al., The Calmodulin Binding Region of the Synaptic Vesicle Protein Mover Is Required for Homomeric Interaction and Presynaptic Targeting. Front Mol Neurosci. 2019;12:249 |
| All: |
2 reference(s) |
|
Analysis Tools
