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Gene Expression Data
Assay Details
Assay
Reference: J:135185 Zhao R, et al., Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice. Dev Biol. 2008 May 15;317(2):614-9
Assay type: RNA in situ
MGI Accession ID: MGI:6383159
Gene symbol: Nkx2-5
Gene name: NK2 homeobox 5
Probe: Nkx2-5 probe16
Probe preparation: labelled with digoxigenin
Results
Specimen 4 Nkx2.5 ventral view G4+/+ G6+/+: embryonic day 8.5 (more )
Note: 8-10 somites.
Structure Level Pattern Image Note
TS13: primary heart field Present Regionally restricted 4Nkx2.5 ventral view G4+/+ G6+/+ Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.
TS13: secondary heart field Present Regionally restricted 4Nkx2.5 ventral view G4+/+ G6+/+ Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.
Specimen 4 Nkx2-5 ventral view G4-/- G6-/-: embryonic day 8.5; Gata4tm1.2Sad/Gata4tm1.2Sad, Gata6tm3.1Sad/Gata6tm3.1Sad (more )
Note: 8-10 somites.
Structure Level Pattern Image Note
TS13: primary heart field Present Regionally restricted 4Nkx2.5 ventral view G4-/- G6-/- Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.
TS13: secondary heart field Present Regionally restricted 4Nkx2.5 ventral view G4-/- G6-/- Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.
Specimen 4 Nkx2-5 (section) G4+/+ G6+/+: embryonic day 8.5 (more )
Note: 8-10 somites.
Structure Level Pattern Image Note
TS13: primary heart field Present Regionally restricted 4Nkx2.5 (section) G4+/+ G6+/+ Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.
TS13: secondary heart field Present Regionally restricted 4Nkx2.5 (section) G4+/+ G6+/+ Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.
Specimen 4 Nkx2-5 (section) G4-/- G6-/-: embryonic day 8.5; Gata4tm1.2Sad/Gata4tm1.2Sad, Gata6tm3.1Sad/Gata6tm3.1Sad (more )
Note: 8-10 somites.
Structure Level Pattern Image Note
TS13: primary heart field Present Regionally restricted 4Nkx2.5 (section) G4-/- G6-/- Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.
TS13: secondary heart field Present Regionally restricted 4Nkx2.5 (section) G4-/- G6-/- Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory