Isl1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:135185 Zhao R, et al., Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice. Dev Biol. 2008 May 15;317(2):614-9
Assay type:	RNA in situ
MGI Accession ID:	MGI:6383156
Gene symbol:	Isl1
Gene name:	ISL1 transcription factor, LIM/homeodomain

Probe:	Isl1 probe32
Probe preparation:	labelled with digoxigenin

Results

Specimen 4 Isl1 E8.5 ventral view G4+/+ G6+/+: embryonic day 8.5 (more

)
Note: 8-10 somites.

Structure	Level	Pattern	Image	Note
TS13: secondary heart field	Present	Regionally restricted	4Isl1 E8.5 ventral view G4+/+ G6+/+	Predominantly expressed in progenitor cells within the second heart field. Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.

Specimen 4 Isl1 E8.5 ventral view G4-/- G6-/-: embryonic day 8.5; Gata4^tm1.2Sad/Gata4^tm1.2Sad, Gata6^tm3.1Sad/Gata6^tm3.1Sad (more

)
Note: 8-10 somites.

Structure	Level	Pattern	Image	Note
TS13: secondary heart field	Present	Regionally restricted	4Isl1 E8.5 ventral view G4-/- G6-/-	Predominantly expressed in progenitor cells within the second heart field. Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.

Specimen 4 Isl1 E8.5 (section) G4+/+ G6+/+: embryonic day 8.5 (more

)
Note: 8-10 somites.

Structure	Level	Pattern	Image	Note
TS13: secondary heart field	Present	Regionally restricted	4Isl1 E8.5 (section) G4+/+ G6+/+	Predominantly expressed in progenitor cells within the second heart field. Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.

Specimen 4 Isl1 E8.5 (section) G4-/- G6-/-: embryonic day 8.5; Gata4^tm1.2Sad/Gata4^tm1.2Sad, Gata6^tm3.1Sad/Gata6^tm3.1Sad (more

)
Note: 8-10 somites.

Structure	Level	Pattern	Image	Note
TS13: secondary heart field	Present	Regionally restricted	4Isl1 E8.5 (section) G4-/- G6-/-	Predominantly expressed in progenitor cells within the second heart field. Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.

Specimen 4 Isl1 E7.5 G4+/+ G6-/-: embryonic day 7.5 (more

)
Note: Early headfold.

Structure	Level	Pattern	Image	Note
TS11: secondary heart field	Present	Regionally restricted	4Isl1 E7.5 G4+/+ G6 +/+	Predominantly expressed in progenitor cells within the second heart field. Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.

Specimen 4 Isl1 E7.5 G4-/- G6-/-: embryonic day 7.5; Gata4^tm1.2Sad/Gata4^tm1.2Sad, Gata6^tm3.1Sad/Gata6^tm3.1Sad (more

)
Note: Early headfold.

Structure	Level	Pattern	Image	Note
TS11: secondary heart field	Present	Regionally restricted	4Isl1 E7.5 G4-/- G6-/-	Predominantly expressed in progenitor cells within the second heart field. Most abundant in two lateral domains of mesoderm that mark cardiac progenitors.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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