Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Pvalbtm1(icre)Ksak
Name:	parvalbumin; targeted mutation 1, Kenji Sakimura
MGI ID:	MGI:6382183
Synonyms:	PV-Cre
Gene:	Pvalb  Location: Chr15:78075314-78090600 bp, - strand  Genetic Position: Chr15, 36.93 cM, cytoband E
Alliance:	Pvalbtm1(icre)Ksak page

Germline Transmission:	Earliest citation of germline transmission: J:279656
Parent Cell Line:	RENKA (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Epitope tag, Recombinase, Reporter) Mutation:    Insertion   Pvalbtm1(icre)Ksak expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Pvalb (MGI:97821)   Mutation details: The targeting construct with iCre-IRES-FLAG-EGFP cDNA followed by FRT flanked neomycin resistance cassette was placed just behind the translational initiation site of the Pvalb gene exon 2 in frame. (J:279656)

Activity:	Tissue activity of this recombinase allele
Driver:	Pvalb (mouse) Summary of all recombinase alleles driven by Pvalb. Alliance mouse Pvalb gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pvalb Mutation:	29 strains or lines available

Original:	J:279656 Inoue M, et al., Rational Engineering of XCaMPs, a Multicolor GECI Suite for In Vivo Imaging of Complex Brain Circuit Dynamics. Cell. 2019 May 16;177(5):1346-1360.e24
All:	1 reference(s)