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Gene Expression Data
Assay Details
Assay
Reference: J:202837 Rowton M, et al., Regulation of mesenchymal-to-epithelial transition by PARAXIS during somitogenesis. Dev Dyn. 2013 Nov;242(11):1332-44
Assay type: RNA in situ
MGI Accession ID: MGI:6382175
Gene symbol: Twist1
Gene name: twist basic helix-loop-helix transcription factor 1
Probe: Twist1 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4 +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: somite Present 4_+/+ Twist1
TS15: unsegmented mesenchyme Present 4_+/+ Twist1
Specimen 4 -/-: embryonic day 9.5; Tcf15tm1Eno/Tcf15tm1Eno (more )
Structure Level Pattern Image Note
TS15: somite Ambiguous Regionally restricted 4_-/- Twist1 Expression was either dramatically reduced or entirely lost in the posterior somites and presomitic mesoderm.
TS15: unsegmented mesenchyme Ambiguous Regionally restricted 4_-/- Twist1 Expression was either dramatically reduced or entirely lost in the posterior somites and presomitic mesoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory