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Gene Expression Data
Assay Details
Assay
Reference: J:194917 Juuri E, et al., Sox2 marks epithelial competence to generate teeth in mammals and reptiles. Development. 2013 Apr;140(7):1424-32
Assay type: RNA in situ
MGI Accession ID: MGI:6382165
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Probe: Sox2 cDNA9
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 2C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dental placode Strong Regionally restricted 2C Expression is strongest in the lingual aspect of the dental epithelium.
TS20: oral epithelium Present 2C
TS20: jaw primordium mesenchyme Trace 2C
TS20: oral region mesenchyme Trace 2C

Specimen 2D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw tooth epithelium Present Regionally restricted 2D Expression is in the lingual dental epithelium.
TS22: oral epithelium Present Regionally restricted 2D Expression is at the lingual side of the tooth germ and continued to the lingual cells of the dental cord and enamel organ.
TS22: lower jaw molar enamel organ Present Regionally restricted 2D Expression is in the outer enamel epithelium.
TS22: lower jaw molar dental lamina Present 2D
TS22: stellate reticulum Present 2D
TS22: lower jaw mesenchyme Trace 2D

Specimen 2E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lower jaw molar epithelium Present Regionally restricted 2E Expression is in the lingual dental epithelium.
TS24: oral epithelium Present Regionally restricted 2E Expression is at the lingual side of the tooth germ and continued to the lingual cells of the dental cord and enamel organ.
TS24: lower jaw molar enamel organ Present Regionally restricted 2E Expression is in the outer enamel epithelium.
TS24: lower jaw molar dental lamina Present 2E
TS24: stellate reticulum Present 2E
TS24: lower jaw mesenchyme Trace 2E
TS24: cervical loop Weak 2E


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory