Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Pdgfrb-FLP1,Cspg4-cre/ERT2)#Bvz
Name:	transgene insertion, Berislav V Zlokovic
MGI ID:	MGI:6382023
Synonyms:	Pdgfrb-Flp;Cspg4-FSF-CreER
Transgene:	Tg(Pdgfrb-FLP1,Cspg4-cre/ERT2)#Bvz  Location: unknown
Alliance:	Tg(Pdgfrb-FLP1,Cspg4-cre/ERT2)#Bvz page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Pdgfrb-FLP1,Cspg4-cre/ERT2)#Bvz expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Cspg4 (MGI:2153093)   Mutation details: Two constructs consisting of one with a mouse Pdgfrb promotor driving Flp recombinase and another carring a Frt-Stop-Frt-CreERT2 cassette under the control of the mouse Cspg4 promoter were co-injected into C57BL/6 blastocysts via pronuclear injection. Five founder pups were identyfied as carrying both transgenes. One unnamed founder line was established and verified. The pound symbol (#) is used when no line name is specified and/or lines are pooled. (J:281538)

Activity:	Tissue activity of this recombinase allele
Driver:	Cspg4 (mouse) Summary of all recombinase alleles driven by Cspg4. Comparative matrix view of recombinase activities Alliance mouse Cspg4 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:281538 Nikolakopoulou AM, et al., Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss. Nat Neurosci. 2019 Jul;22(7):1089-1098
All:	2 reference(s)