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Gene Expression Data
Assay Details
Assay
Reference: J:130185 Ellsworth BS, et al., Mechanisms underlying pituitary hypoplasia and failed cell specification in Lhx3-deficient mice. Dev Biol. 2008 Jan 1;313(1):118-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6380632
Gene symbol: Pitx1
Gene name: paired-like homeodomain transcription factor 1
Antibody: anti-PITX1
Detection system: fluorescein
Results
Specimen 1A: embryonic day 11.5 (more )
Note: Double labeled: green - Pitx1; red - BrdU.
Structure Level Pattern Image Note
TS19: future pituitary Present 1A
Specimen 1B: embryonic day 11.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Note: Double labeled: green - Pitx1; red - BrdU.
Structure Level Pattern Image Note
TS19: future pituitary Present 1B Morphology of mutant pituitary is noticeably different from normal by E11.5.
Specimen 1C: embryonic day 12.5 (more )
Note: Double labeled: green - Pitx1; red - BrdU.
Structure Level Pattern Image Note
TS20: pituitary gland Present 1C
Specimen 1D: embryonic day 12.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Note: Double labeled: green - Pitx1; red - BrdU.
Structure Level Pattern Image Note
TS20: pituitary gland Present 1D Morphology is significantly different from normal.
Specimen E14.5 Wild type not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pituitary gland Present
Specimen E14.5 Mutant not shown: embryonic day 14.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Structure Level Pattern Image Note
TS22: pituitary gland Present Morphology is significantly different from normal.
Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pituitary gland Present 5A
Specimen 5B: embryonic day 12.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Structure Level Pattern Image Note
TS20: pituitary gland Present 5B Authors report normal expression at E12.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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