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Gene Expression Data
Assay Details
Assay
Reference: J:34321 White FA, et al., Synchronous onset of NGF and TrkA survival dependence in developing dorsal root ganglia. J Neurosci. 1996 Aug 1;16(15):4662-72
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6379756
Gene symbol: Ntrk1
Gene name: neurotrophic tyrosine kinase, receptor, type 1
Antibody: rtrkA.EX
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: Fixtative was 3% paraformaldehyde/15% picric acid.
Results
Specimen 3 E11.5: embryonic day 11.5 (more )
Note: Camera lucida reconstructions.
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 3_E11.5 TrkA
TS19: hindlimb bud Present Regionally restricted 3_E11.5 TrkA Expression is in fibers are penetrating into the central region of the proximal hindlimb, and is absent distally.
Specimen 3 E13.5: embryonic day 13.5 (more )
Note: Camera lucida reconstructions.
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present 3_E13.5 TrkA
TS21: hindlimb Present Regionally restricted 3_E13.5 TrkA Expression is in fibers that are penetrating into the central region of the proximal hindlimb and are approaching cutaneous target fields in proximal hindlimb. Expression is absent in the distal cutaneous targets.
Specimen 3 E15.5: embryonic day 15.5 (more )
Note: Camera lucida reconstructions.
Structure Level Pattern Image Note
TS23: dorsal root ganglion Present 3_E15.5 TrkA
TS23: hindlimb Present Regionally restricted 3_E15.5 TrkA Expression is in fibers that are penetrating into the hindlimb including arborization in the entire cutaneous epithelium.
Specimen 4 E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Strong 4_TrkA E11.5 bottom
Specimen 4 E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Strong 4_TrkA E13.5 bottom
Specimen not shown E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk nerve Present Regionally restricted Expression is in axons projecting into dorsal and lateral cutaneous epithelium of the lower trunk.
Specimen not shown E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: spinal cord gray matter Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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