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Gene Expression Data
Assay Details
Assay
Reference: J:276389 Li M, et al., Ythdf2-mediated m(6)A mRNA clearance modulates neural development in mice. Genome Biol. 2018 May 31;19(1):69
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6379686
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2 (ab79351)
Detection system: Secondary antibody
Results
Specimen 3a WT E12.5: embryonic day 12.5 (more )
Note: Double labeled: red - Sox2; green - Eomes (assay MGI:6379685).
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 3a E12.5 WT Tbr2 , 3a E12.5 WT Sox2/Tbr2 Expression is in apical progenitor cells.
Specimen 3a Ythdf2+/- E12.5: embryonic day 12.5; Ythdf2em1.1Klng/Ythdf2+ (more )
Note: Double labeled: red - Sox2; green - Eomes (assay MGI:6379685).
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 3a E12.5 +/- Sox2/Tbr2 , 3a E12.5 +/- Tbr2 Expression in this mutant is the same as in wild-type littermates.
Specimen 3a Ythdf2-/- E12.5: embryonic day 12.5; Ythdf2em1.1Klng/Ythdf2em1.1Klng (more )
Note: Double labeled: red - Sox2; green - Eomes (assay MGI:6379685).
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 3a E12.5 -/- Sox2/Tbr2 , 3a E12.5 -/- Tbr2 Expression in this mutant is the same as in wild-type littermates.
Specimen 3a WT E14.5: embryonic day 14.5 (more )
Note: Double labeled: red - Sox2; green - Eomes (assay MGI:6379685).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 3a E14.5 WT Sox2/Tbr2 , 3a E14.5 WT Tbr2 Expression is in apical progenitor cells.
Specimen 3a Ythdf2+/- E14.5: embryonic day 14.5; Ythdf2em1.1Klng/Ythdf2+ (more )
Note: Double labeled: red - Sox2; green - Eomes (assay MGI:6379685).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 3a E14.5 +/- Sox2/Tbr2 , 3a E14.5 +/- Tbr2 Expression in this mutant is the same as in wild-type littermates.
Specimen 3a Ythdf2-/- E14.5: embryonic day 14.5; Ythdf2em1.1Klng/Ythdf2em1.1Klng (more )
Note: Double labeled: red - Sox2; green - Eomes (assay MGI:6379685).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 3a E14.5 -/- Sox2/Tbr2 , 3a E14.5 -/- Tbr2 Expression in this mutant is the same as in wild-type littermates.
Specimen 3c WT E12.5: embryonic day 12.5 (more )
Note: Double labeled: red - Sox2; green - Phosphohistone 3.
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 3c E12.5 Sox2 WT Expression is in apical progenitor cells.
Specimen 3c Ythdf2+/- E12.5: embryonic day 12.5; Ythdf2em1.1Klng/Ythdf2+ (more )
Note: Double labeled: red - Sox2; green - Phosphohistone 3.
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 3c E12.5 Sox2 +/- Expression in this mutant is the same as in wild-type littermates.
Specimen 3c Ythdf2-/- E12.5: embryonic day 12.5; Ythdf2em1.1Klng/Ythdf2em1.1Klng (more )
Note: Double labeled: red - Sox2; green - Phosphohistone 3.
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 3c E12.5 Sox2 -/- Expression in this mutant is the same as in wild-type littermates.
Specimen 3c WT E14.5: embryonic day 14.5 (more )
Note: Double labeled: red - Sox2; green - Phosphohistone 3.
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 3c E14.5 Sox2 WT Expression is in apical progenitor cells.
Specimen 3c Ythdf2+/- E14.5: embryonic day 14.5; Ythdf2em1.1Klng/Ythdf2+ (more )
Note: Double labeled: red - Sox2; green - Phosphohistone 3.
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 3c E14.5 Sox2 +/- Expression in this mutant is the same as in wild-type littermates.
Specimen 3c Ythdf2-/- E14.5: embryonic day 14.5; Ythdf2em1.1Klng/Ythdf2em1.1Klng (more )
Note: Double labeled: red - Sox2; green - Phosphohistone 3.
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 3c E14.5 Sox2 -/- Expression in this mutant is the same as in wild-type littermates.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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