Tg(Trpm8-HBEGF/EGFP)M8Dmck
Transgene Detail
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| Symbol: |
Tg(Trpm8-HBEGF/EGFP)M8Dmck |
| Name: |
transgene insertion M8, David McKemy |
| MGI ID: |
MGI:6379569 |
| Synonyms: |
Tg(Trpm8-DTR/EGFP)M8Dmck, Trpm8DTR |
| Transgene: |
Tg(Trpm8-HBEGF/EGFP)M8Dmck Location: unknown
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| Alliance: |
Tg(Trpm8-HBEGF/EGFP)M8Dmck page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Trpm8-HBEGF/EGFP)M8Dmck expresses
2 genes
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| monkey |
HBEGF |
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| mouse |
Trpm8 (MGI:2181435) |
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Mutation details: A 130-200 kbp bacterial artificial chromosome (BAC) RPC1-22 clone 553 H3 containing the entire ~80 kbp mouse Trpm8 gene was modified to insert a simian diphtheria toxin receptor / enhanced green fluorescent protein fusion gene sequence (DTR/EGFP) followed by an SV40 polyA sequence into exon 2 of Trpm8 locus on the BAC (disrupting the Trpm8 coding region). No other loci on the BAC were altered. The BAC may also include the Ugt1a2, Dnajb3, Ugt1a1, Mroh2a, Hjurp and Spp2 loci.
(J:194264)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:194264 Knowlton WM, et al., A sensory-labeled line for cold: TRPM8-expressing sensory neurons define the cellular basis for cold, cold pain, and cooling-mediated analgesia. J Neurosci. 2013 Feb 13;33(7):2837-48 |
| All: |
1 reference(s) |
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Analysis Tools
