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Gene Expression Data
Assay Details
Assay
Reference: J:144178 Couillard M, et al., C-myc as a modulator of renal stem/progenitor cell population. Dev Dyn. 2009 Feb;238(2):405-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6379571
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Antibody: anti-Six2
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5F: embryonic day 12.5; Myctm2Fwa/Myc+ (more )
Structure Level Pattern Image Note
TS20: cap mesenchyme Present Regionally restricted 5F Expression is on the dorsal side of the ureteric bud.

Specimen 5G: embryonic day 12.5; Bmp7tm6(cre)Rob/Bmp7+, Myctm2Fwa/Myctm2Fwa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: cap mesenchyme Present 5G Expression in this mutant is the same as in control embryos.

Specimen 5H: embryonic day 15.5; Myctm2Fwa/Myc+ (more )
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted 5H Expression is in multiple layers of condensed cap mesenchyme surrounding ureteric bud tips.

Specimen 5I: embryonic day 15.5; Bmp7tm6(cre)Rob/Bmp7+, Myctm2Fwa/Myctm2Fwa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted 5I Expression is in one to two layers of condensed cap mesenchyme surrounding ureteric bud tips and expression was reduced by 30% compared to controls.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory