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Gene Expression Data
Assay Details
Assay
Reference: J:144178 Couillard M, et al., C-myc as a modulator of renal stem/progenitor cell population. Dev Dyn. 2009 Feb;238(2):405-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6379570
Gene symbol: Pax2
Gene name: paired box 2
Antibody: anti-Pax2
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5A: embryonic day 12.5; Myctm2Fwa/Myc+ (more )
Structure Level Pattern Image Note
TS20: nephric duct Present Regionally restricted 5A Expression is in ureteric bud branches.
TS20: mesenchyme of metanephros Present Regionally restricted 5A Expression is in condensed mesenchyme on the dorsal side of the ureteric bud.
TS20: renal vesicle Strong Regionally restricted 5A Expression is on the ventral side in ureteric bud and metanephric mesenchyme derivatives.
Specimen 5B: embryonic day 12.5; Bmp7tm6(cre)Rob/Bmp7+, Myctm2Fwa/Myctm2Fwa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: mesenchyme of metanephros Present Regionally restricted 5B Expression in this mutant is similar as in control embryos.
TS20: nephric duct Present Regionally restricted 5B Expression in this mutant is similar as in control embryos.
TS20: renal vesicle Present Regionally restricted 5B Expression in this mutant is similar as in control embryos.
Specimen 5C: embryonic day 15.5; Myctm2Fwa/Myc+ (more )
Structure Level Pattern Image Note
TS23: nephric duct Present Regionally restricted 5C Expression is in ureteric bud.
TS23: cap mesenchyme Present 5C
TS23: comma-shaped body Present 5C
TS23: renal vesicle Present 5C
TS23: s-shaped body Present 5C
Specimen 5D: embryonic day 15.5; Bmp7tm6(cre)Rob/Bmp7+, Myctm2Fwa/Myctm2Fwa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: comma-shaped body Present Regionally restricted 5D Expression in this mutant is similar as in control embryos.
TS23: nephric duct Present Regionally restricted 5D Expression in this mutant is similar as in control embryos.
TS23: renal vesicle Present Regionally restricted 5D Expression in this mutant is similar as in control embryos.
TS23: s-shaped body Present Regionally restricted 5D Expression in this mutant is similar as in control embryos.
TS23: cap mesenchyme Present 5D Quantification of expression showed no statistical difference but expression appeared reduced in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory