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Gene Expression Data
Assay Details
Assay
Reference: J:144178 Couillard M, et al., C-myc as a modulator of renal stem/progenitor cell population. Dev Dyn. 2009 Feb;238(2):405-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6379567
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67 (NCL-Ki67p)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4A: embryonic day 12.5; Myctm2Fwa/Myc+ (more )
Structure Level Pattern Image Note
TS20: cap mesenchyme Present Regionally restricted 4A Expression is in dividing cells.
TS20: mesenchyme of metanephros Present Regionally restricted 4A Expression is in dividing cells.
TS20: nephric duct Present Regionally restricted 4A Expression is in dividing cells.
Specimen 4B: embryonic day 12.5; Bmp7tm6(cre)Rob/Bmp7+, Myctm2Fwa/Myctm2Fwa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: cap mesenchyme Present Regionally restricted 4B Expression in dividing cells is similar as in control embryos.
TS20: mesenchyme of metanephros Present Regionally restricted 4B Expression in dividing cells is similar as in control embryos.
TS20: nephric duct Present Regionally restricted 4B Expression in dividing cells is similar as in control embryos.
Specimen 4C: embryonic day 15.5; Myctm2Fwa/Myc+ (more )
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted 4C Expression is concentrated over the low lateral edge.
TS23: comma-shaped body Present 4C
TS23: pretubular aggregate Present 4C
TS23: renal vesicle Present 4C
TS23: s-shaped body Present 4C
Specimen 4D: embryonic day 15.5; Bmp7tm6(cre)Rob/Bmp7+, Myctm2Fwa/Myctm2Fwa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted 4D Expression over the low lateral edge is reduced by 19% in this mutant compared to control embryos.
TS23: comma-shaped body Present 4D Expression in this mutant is similar as in control embryos.
TS23: pretubular aggregate Present 4D Expression in this mutant is similar as in control embryos.
TS23: renal vesicle Present 4D Expression in this mutant is similar as in control embryos.
TS23: s-shaped body Present 4D Expression in this mutant is similar as in control embryos.
Specimen 4E: embryonic day 16.5; Myctm2Fwa/Myc+ (more )
Structure Level Pattern Image Note
TS24: cap mesenchyme Present Regionally restricted 4E Expression is concentrated over the low lateral edge.
TS24: comma-shaped body Present 4E
TS24: pretubular aggregate Present 4E
TS24: renal vesicle Present 4E
TS24: s-shaped body Present 4E
Specimen 4F: embryonic day 16.5; Bmp7tm6(cre)Rob/Bmp7+, Myctm2Fwa/Myctm2Fwa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: cap mesenchyme Present Regionally restricted 4F Expression over the low lateral edge is reduced by 30% in this mutant compared to control embryos.
TS24: comma-shaped body Present 4F Expression in this mutant is similar as in control embryos.
TS24: pretubular aggregate Present 4F Expression in this mutant is similar as in control embryos.
TS24: renal vesicle Present 4F Expression in this mutant is similar as in control embryos.
TS24: s-shaped body Present 4F Expression in this mutant is similar as in control embryos.
Specimen 4G: embryonic day 18.5; Myctm2Fwa/Myc+ (more )
Structure Level Pattern Image Note
TS26: cap mesenchyme Present Regionally restricted 4G Expression is concentrated over the low lateral edge.
TS26: comma-shaped body Present 4G
TS26: pretubular aggregate Present 4G
TS26: renal vesicle Present 4G
TS26: s-shaped body Present 4G
Specimen 4H: embryonic day 18.5; Bmp7tm6(cre)Rob/Bmp7+, Myctm2Fwa/Myctm2Fwa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cap mesenchyme Present Regionally restricted 4H Expression over the low lateral edge is reduced by 36% in this mutant compared to control embryos.
TS26: comma-shaped body Present 4H Expression in this mutant is similar as in control embryos.
TS26: pretubular aggregate Present 4H Expression in this mutant is similar as in control embryos.
TS26: renal vesicle Present 4H Expression in this mutant is similar as in control embryos.
TS26: s-shaped body Present 4H Expression in this mutant is similar as in control embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory