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Gene Expression Data
Assay Details
Assay
Reference: J:144178 Couillard M, et al., C-myc as a modulator of renal stem/progenitor cell population. Dev Dyn. 2009 Feb;238(2):405-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6379399
Gene symbol: Myc
Gene name: myelocytomatosis oncogene
Antibody: anti-c-Myc
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A: embryonic day 13.5; Myctm2Fwa/Myc+ (more )
Structure Level Pattern Image Note
TS21: cap mesenchyme Present Regionally restricted 3A Expression is in most cells.
TS21: pretubular aggregate Present Regionally restricted 3A Expression is in most cells.
TS21: comma-shaped body Weak Regionally restricted 3A Expression is mosaic.
TS21: s-shaped body Weak Regionally restricted 3A Expression is mosaic.
TS21: collecting duct Present Regionally restricted 3A Expression is cytoplasmic in the ureteric bud epithelium.
Specimen 3B: embryonic day 13.5; Bmp7tm6(cre)Rob/Bmp7+, Myctm2Fwa/Myctm2Fwa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: cap mesenchyme Present 3B Expression in this mutant is the same as in wild-type embryos.
TS21: pretubular aggregate Present 3B Expression in this mutant is the same as in wild-type embryos.
TS21: collecting duct Present 3B Expression in the ureteric bud epithelium of this mutant is the same as in wild-type embryos.
TS21: comma-shaped body Weak 3B Expression in this mutant is the same as in wild-type embryos.
TS21: s-shaped body Weak 3B Expression in this mutant is the same as in wild-type embryos.
Specimen 3C: embryonic day 14.5; Myctm2Fwa/Myc+ (more )
Structure Level Pattern Image Note
TS22: cap mesenchyme Present Regionally restricted 3C Expression is in most cells.
TS22: pretubular aggregate Present Regionally restricted 3C Expression is in most cells.
TS22: comma-shaped body Present Regionally restricted 3C Expression is mosaic.
TS22: s-shaped body Present Regionally restricted 3C Expression is mosaic.
TS22: collecting duct Present Regionally restricted 3C Expression is cytoplasmic in the ureteric bud epithelium.
Specimen 3D: embryonic day 14.5; Bmp7tm6(cre)Rob/Bmp7+, Myctm2Fwa/Myctm2Fwa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: cap mesenchyme Weak Regionally restricted 3D There is a decrease in positive cell populations.
TS22: comma-shaped body Present Regionally restricted 3D Most of this structure exhibited similar expression as seen in control embryos.
TS22: pretubular aggregate Present Regionally restricted 3D Most of this structure exhibited similar expression as seen in control embryos.
TS22: renal vesicle Present Regionally restricted 3D Most of this structure exhibited similar expression as seen in control embryos.
TS22: s-shaped body Present Regionally restricted 3D Most of this structure exhibited similar expression as seen in control embryos.
TS22: collecting duct Present Regionally restricted 3D Expression in the ureteric bud epithelium of this mutant is the same as in wild-type embryos.
Specimen 3E: embryonic day 15.5; Myctm2Fwa/Myc+ (more )
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted 3E Expression is in most cells.
TS23: pretubular aggregate Present Regionally restricted 3E Expression is in most cells.
TS23: comma-shaped body Present Regionally restricted 3E Expression is mosaic.
TS23: s-shaped body Present Regionally restricted 3E Expression is mosaic.
TS23: collecting duct Present Regionally restricted 3E Expression is cytoplasmic in the ureteric bud epithelium.
Specimen 3F: embryonic day 15.5; Bmp7tm6(cre)Rob/Bmp7+, Myctm2Fwa/Myctm2Fwa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cap mesenchyme Weak Regionally restricted 3F There is a large decrease in positive cell populations.
TS23: comma-shaped body Present Regionally restricted 3F Most of this structure exhibited similar expression as seen in control embryos.
TS23: pretubular aggregate Present Regionally restricted 3F Most of this structure exhibited similar expression as seen in control embryos.
TS23: renal vesicle Present Regionally restricted 3F Most of this structure exhibited similar expression as seen in control embryos.
TS23: s-shaped body Present Regionally restricted 3F Most of this structure exhibited similar expression as seen in control embryos.
TS23: collecting duct Present Regionally restricted 3F Expression in the ureteric bud epithelium of this mutant is the same as in wild-type embryos.
Specimen 3G: embryonic day 18.5; Myctm2Fwa/Myc+ (more )
Structure Level Pattern Image Note
TS26: cap mesenchyme Present Regionally restricted 3G Expression is in most cells.
TS26: pretubular aggregate Present Regionally restricted 3G Expression is in most cells.
TS26: comma-shaped body Present Regionally restricted 3G Expression is mosaic.
TS26: s-shaped body Present Regionally restricted 3G Expression is mosaic.
TS26: collecting duct Present Regionally restricted 3G Expression is cytoplasmic in the ureteric bud epithelium.
Specimen 3H: embryonic day 18.5; Bmp7tm6(cre)Rob/Bmp7+, Myctm2Fwa/Myctm2Fwa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cap mesenchyme Weak Regionally restricted 3H There is a large decrease in positive cell populations.
TS26: comma-shaped body Present Regionally restricted 3H Most of this structure exhibited similar expression as seen in control embryos.
TS26: pretubular aggregate Present Regionally restricted 3H Most of this structure exhibited similar expression as seen in control embryos.
TS26: renal vesicle Present Regionally restricted 3H Most of this structure exhibited similar expression as seen in control embryos.
TS26: s-shaped body Present Regionally restricted 3H Most of this structure exhibited similar expression as seen in control embryos.
TS26: collecting duct Present Regionally restricted 3H Expression in the ureteric bud epithelium of this mutant is the same as in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory