About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:276611 Vatsa N, et al., Down-Regulation of miRNA-708 Promotes Aberrant Calcium Signaling by Targeting Neuronatin in a Mouse Model of Angelman Syndrome. Front Mol Neurosci. 2019;12:35
Assay type: RT-PCR
MGI Accession ID: MGI:6379309
Gene symbol: Mir708
Gene name: microRNA 708
Probe: Mir708-pA, Mir708-pB
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Samples were normalized against RNU6.
Results
Image: 1A ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
Ube3a (m+/p+) P10 TS28: cerebral cortex Present Not Specified; total RNA Not Specified Not Specified
Ube3a (m-/p+) P10 TS28: cerebral cortex Weak (a) Not Specified; total RNA involves: 129S7/SvEvBrd Ube3atm1Alb/Ube3a+Not Specified
Ube3a (m+/p+) P60 TS28: cerebral cortex Present Not Specified; total RNA Not Specified Not Specified
Ube3a (m-/p+) P60 TS28: cerebral cortex Weak (b) Not Specified; total RNA involves: 129S7/SvEvBrd Ube3atm1Alb/Ube3a+Not Specified
Notes:
(a) There was a significant reduction of expression level in Angelman Syndrome mice samples with respect to wild type controls. At P10 expression was reduced to about 30%.
(b) There was a significant reduction of expression level in Angelman Syndrome mice samples with respect to wild type controls. At P60 expression was reduced to about 50%.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory