Bmp2 RT-PCR Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:141834 Singh AP, et al., Influences of reduced expression of maternal bone morphogenetic protein 2 on mouse embryonic development. Sex Dev. 2008;2(3):134-41
Assay type:	RT-PCR
MGI Accession ID:	MGI:6379305
Gene symbol:	Bmp2
Gene name:	bone morphogenetic protein 2

Probe:

Mm01340178_m1

Results

Image: 6B

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Amount	Genetic Background	Mutant Allele(s)	Sex	Note
+/+	E9.5	TS15: embryo	Present	Not Specified	involves: 129S7/SvEvBrd * C57BL/6J		Not Specified	Posterior half of embryos.
fn/+	E9.5	TS15: embryo	Weak	Not Specified	involves: 129S7/SvEvBrd * C57BL/6J	Bmp2^tm1Mis/Bmp2⁺	Not Specified	Posterior half of embryos.
+/-	E9.5	TS15: embryo	Weak (a)	Not Specified	involves: 129S7/SvEvBrd * C57BL/6J	Bmp2^tm1Brd/Bmp2⁺	Not Specified	Posterior half of embryos.
fn/fn	E9.5	TS15: embryo	Trace (b)	Not Specified	involves: 129S7/SvEvBrd * C57BL/6J	Bmp2^tm1Mis/Bmp2^tm1Mis	Not Specified	Posterior half of embryos.
fn/-	E9.5	TS15: embryo	Trace (c)	Not Specified	involves: 129S7/SvEvBrd * C57BL/6J	Bmp2^tm1Brd/Bmp2^tm1Mis	Not Specified	Posterior half of embryos.

Notes:
(a) Expression level 10% relative to wild type.
(b) Expression in posterior half dramatically reduced: 7% compared to wild type
(c) Expression levels slightly lower (4% compared to wild type) than those of fn/fn embryos.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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