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Gene Expression Data
Assay Details
Assay
Reference: J:122558 Yu L, et al., Shox2 is required for chondrocyte proliferation and maturation in proximal limb skeleton. Dev Biol. 2007 Jun 15;306(2):549-59
Assay type: RNA in situ
MGI Accession ID: MGI:6377409
Gene symbol: Shox2
Gene name: SHOX homeobox 2
Probe: Shox2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud mesenchyme Present Regionally restricted 1A Stronger expression in dorsal regions.

Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 1B Expression restricted to proximal limb mesenchyme, with stronger expression remaining in dorsal regions.

Specimen 1C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future arm mesenchyme Present Regionally restricted 1C Strong expression in proximal limb mesenchyme associated with stylopodial cartilaginous elements. Relatively weak expression in mesenchymal tissues surrounding future zeugopodial condensations.

Specimen 1D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: upper arm rest of mesenchyme Present Regionally restricted 1D Expression in mesenchyme of proximal limb surrounding cartilaginous elements.
TS20: humerus pre-cartilage condensation Weak Regionally restricted 1D Weak expression in chondrocytes in both ends of humerus.

Specimen 1E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Present Regionally restricted 1E Expression in immature (proliferating) chondrocytes.
TS21: upper arm rest of mesenchyme Present Regionally restricted 1E Strong expression in perichondrium of humerus. Expression downregulated in surrounding connective tissue .

Specimen 1F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present Regionally restricted 1F Expression in immature (proliferating) chondrocytes.
TS22: upper arm rest of mesenchyme Present Regionally restricted 1F Strong expression in perichondrium of humerus. Expression downregulated in surrounding connective tissue .


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory