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Gene Expression Data
Assay Details
Assay
Reference: J:222465 Borello U, et al., Sp8 and COUP-TF1 reciprocally regulate patterning and Fgf signaling in cortical progenitors. Cereb Cortex. 2014 Jun;24(6):1409-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6377254
Gene symbol: Sp8
Gene name: trans-acting transcription factor 8
Antibody: Anti-Sp8
Results
Specimen S1A: embryonic day 12.5; Sp8tm2Smb/Sp8+, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: neocortex Present Regionally restricted S1A Expression was detected in the dorsomedial pallium.
TS20: lateral ganglionic eminence Present S1A
Specimen S1B: embryonic day 12.5; Sp8tm2Smb/Sp8tm2Smb, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: neocortex Absent S1B
TS20: lateral ganglionic eminence Present Single cells S1B Only a few remaining cells remain in the lateral ganglionic eminence of the conditional mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory