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Gene Expression Data
Assay Details
Assay
Reference: J:222465 Borello U, et al., Sp8 and COUP-TF1 reciprocally regulate patterning and Fgf signaling in cortical progenitors. Cereb Cortex. 2014 Jun;24(6):1409-21
Assay type: RNA in situ
MGI Accession ID: MGI:6377237
Gene symbol: Nr2f1
Gene name: nuclear receptor subfamily 2, group F, member 1
Probe: COUP-TF1
Probe preparation: Antisense RNA
Results
Specimen 1C: embryonic day 12.5; Sp8tm2Smb/Sp8+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: neocortex Present Graded 1C Expression was detected in a caudoventral high, rostral-dorsal low gradient in the pallium.

Specimen 1D: embryonic day 12.5; Sp8tm2Smb/Sp8tm2Smb, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: neocortex Present Regionally restricted 1D In the conditional mutant, the expression is expanded rostrally and dorsomedially within the pallium.

Specimen 1E: embryonic day 12.5; Sp8tm2Smb/Sp8+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: neocortex Present Graded 1E Expression was detected in a ventral high, dorsal low gradient in the pallium.

Specimen 1F: embryonic day 12.5; Sp8tm2Smb/Sp8tm2Smb, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: neocortex Present Regionally restricted 1F In the conditional mutant, the expression is expanded dorsomedially within the pallium.

Specimen 1G: embryonic day 12.5; Sp8tm2Smb/Sp8+, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: neocortex Present Graded 1G Expression was detected in a ventral high, dorsal low gradient in the pallium.

Specimen 1H: embryonic day 12.5; Sp8tm2Smb/Sp8tm2Smb, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: neocortex Present Graded 1H Expression was not substantially changed from the control.

Specimen S3A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neocortex Present Graded S3A Expression was graded in dorsomedial pallium.

Specimen S3C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neocortex Present Graded S3C Expression was graded in dorsomedial pallium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory