Tg(HBA-CD59)1Jha
Transgene Detail
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| Symbol: |
Tg(HBA-CD59)1Jha |
| Name: |
transgene insertion 1, Jose A Halperin |
| MGI ID: |
MGI:6376203 |
| Synonyms: |
hCD59WT |
| Transgene: |
Tg(HBA-CD59)1Jha Location: unknown
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| Alliance: |
Tg(HBA-CD59)1Jha page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(HBA-CD59)1Jha expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
CD59 (966) |
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Mutation details: The ~7 kb transgene is designed with the human locus control region (LCR) and the alpha globin (HBA) gene promoter driving expression of wild-type human CD59 antigen (CD59) cDNA.
(J:280723)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:280723 Sahoo R, et al., A distinctive histidine residue is essential for in vivo glycation-inactivation of human CD59 transgenically expressed in mice erythrocytes: Implications for human diabetes complications. Am J Hematol. 2017 Nov;92(11):1198-1203 |
| All: |
1 reference(s) |
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Analysis Tools
