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Gene Expression Data
Assay Details
Assay
Reference: J:35122 Imaizumi-Scherrer T, et al., Accumulation in fetal muscle and localization to the neuromuscular junction of cAMP-dependent protein kinase A regulatory and catalytic subunits RI alpha and C alpha. J Cell Biol. 1996 Sep;134(5):1241-54
Assay type: RNA in situ
MGI Accession ID: MGI:6370036
Gene symbol: Prkar1a
Gene name: protein kinase, cAMP dependent regulatory, type I, alpha
Probe: RI-alpha cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2B: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: intercostal muscle Strong Regionally restricted 2B right bottom , 2B right top , 2B right middle , 2B left A strong signal was limited to stripes across the muscle tissue.
Specimen 4 center: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: tibialis anterior Strong Regionally restricted 4_center Expression was detected in the neuromuscular junctions.
Specimen 5 control left: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: tibialis anterior Strong Regionally restricted 5_RI alpha control left
Specimen 5 control center: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: tibialis anterior Strong Regionally restricted 5_RI alpha control center
Specimen 5 control right: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: tibialis anterior Strong Regionally restricted 5_RI alpha control right
Specimen 6 12d: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS21: skeletal muscle Present Regionally restricted 6_12d lower left Expression was diffuse in the throat region, but the neck muscles were well defined.
Specimen 6 14d: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: neck muscle Weak 6_14d lower right Expression was weaker in the back of the neck and throat region compared to E12.0 and has become more discrete.
Specimen 7 RI-alpha: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: diaphragm Present Regionally restricted 7_RI alpha Expression was detected in two patches corresponding to the oval distribution of neuromuscular junctions.
TS24: intercostal muscle Present Regionally restricted 7_RI alpha inset , 7_RI alpha Expression was detected in the junctions running along the center of the ventral intercostal muscles. Signal outside of the stripes remains weak, even after long exposure.
Specimen 8 RI-alpha: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: eye muscle Present 8_RI alpha
TS24: trigeminal ganglion Present 8_RI alpha
TS24: neck muscle Present Regionally restricted 8_RI alpha Expression was detected in throat muscles.
TS24: brain Weak 8_RI alpha
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory