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Gene Expression Data
Assay Details
Assay
Reference: J:233398 Wu RC, et al., Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis. Mol Endocrinol. 2015 Sep;29(9):1334-46
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6369824
Gene symbol: Amh
Gene name: anti-Mullerian hormone
Results
Specimen 6A Control: postnatal day 10; Arid4btm1.1Mywu/Arid4b+, Tg(Amh-cre)8815Reb/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Weak Regionally restricted 6A Expression was weak in immature Sertoli cells.
Specimen 6B Arid4bSCKO: postnatal day 10; Arid4btm1Alb/Arid4btm1.1Mywu, Tg(Amh-cre)8815Reb/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 6B Expression of the immature Sertoli cell marker Amh was detected in the conditional mutant.
Specimen 6C Control: postnatal day 20; Arid4btm1.1Mywu/Arid4b+, Tg(Amh-cre)8815Reb/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Absent 6C
Specimen 6D Arid4bSCKO: postnatal day 20; Arid4btm1Alb/Arid4btm1.1Mywu, Tg(Amh-cre)8815Reb/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 6D Expression of the immature Sertoli cell marker Amh was detected in the conditional mutant.
Specimen 6E Control: postnatal day 30; Arid4btm1.1Mywu/Arid4b+, Tg(Amh-cre)8815Reb/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Absent 6E
Specimen 6F Arid4bSCKO: postnatal day 30; Arid4btm1Alb/Arid4btm1.1Mywu, Tg(Amh-cre)8815Reb/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Weak 6F Expression of the immature Sertoli cell marker Amh remained detectable with decreased intensity in the conditional mutant.
Specimen 6G Control: postnatal day 42; Arid4btm1.1Mywu/Arid4b+, Tg(Amh-cre)8815Reb/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Absent 6G
Specimen 6H Arid4bSCKO: postnatal day 42; Arid4btm1Alb/Arid4btm1.1Mywu, Tg(Amh-cre)8815Reb/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Weak 6H Expression of the immature Sertoli cell marker Amh remained detectable with decreased intensity in the conditional mutant.
Specimen 6I/K,M,O Control: postnatal day 20; Arid4btm1.1Mywu/Arid4b+, Tg(Amh-cre)8815Reb/0 (more )
Note: Conditional mutant. Double labeled: red - Amh; green - Gcna (assay MGI:6369818).
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Absent 6I , 6O , 6K , 6M Expression of the immature Sertoli cell marker Amh has largely been turned off in the control testis. Whereas germ cells labeled with Gcna were present in all seminiferous tubules of the control testis.
Specimen 6J/L,N,P Arid4bSCKO: postnatal day 20; Arid4btm1Alb/Arid4btm1.1Mywu, Tg(Amh-cre)8815Reb/0 (more )
Note: Conditional mutant. Double labeled: red - Amh; green - Gcna (assay MGI:6369818).
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 6P , 6J , 6L , 6N No germ cells (Gcna positive) were produced in the tubules containing immature Sertoli cells (Amh positive).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory