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Ormdl3em1Quli
Endonuclease-mediated Allele Detail
Summary
Symbol: Ormdl3em1Quli
Name: ORM1-like 3 (S. cerevisiae); endonuclease-mediated mutation 1, Qiji Liu
MGI ID: MGI:6369059
Synonyms: Ormdl3-
Gene: Ormdl3  Location: Chr11:98472120-98478071 bp, - strand  Genetic Position: Chr11, 62.07 cM
Alliance: Ormdl3em1Quli page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Not Specified
    A TALEN mutagenesis was used to introduce a truncated mutation within the third exon of Ormdl3 gene. (J:251260)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ormdl3 Mutation:  10 strains or lines available
References
Original:  J:251260 Dang J, et al., ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6alpha-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway. J Immunol. 2017 Sep 1;199(5):1647-1659
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory