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Gene Expression Data
Assay Details
Assay
Reference: J:251548 Moon EH, et al., Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia. Cardiovasc Res. 2015 Mar 1;105(3):353-60
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6367638
Gene symbol: Tmem100
Gene name: transmembrane protein 100
Reporter: lacZ
Direct Detection
Assay notes: Fix: 1% formaldehyde, 0.2% glutaraldehyde.
Results
Specimen 1Ai: embryonic day 15.5; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS23: coronary artery Absent 1Ai

Specimen 1Aii: embryonic day 17.5; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS25: coronary artery Present 1Aii

Specimen 1Aiii: embryonic day 18.5; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS26: coronary artery Present 1Aiii

Specimen 1Aiv: postnatal day 2; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS27: coronary artery Present 1Aiv

Specimen 1Av: postnatal day 8; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS28: coronary artery Present 1Av

Specimen 1Avi: postnatal day 21; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS28: coronary artery Absent 1Avi Expression in the coronary arteries disappeared at weaning age.

Specimen 1Bi: embryonic day 15.5; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS23: pulmonary artery Present 1Bi

Specimen 1Bii: embryonic day 17.5; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS25: pulmonary artery Present 1Bii
TS25: lung vascular element Present 1Bii As development proceeded, expression extended to capillaries.

Specimen 1Biii: postnatal day 2; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS27: pulmonary artery Present 1Biii
TS27: lung vascular element Present 1Biii As development proceeded, expression extended to capillaries.

Specimen 1Biv: postnatal week 6; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS28: lung vascular element Present 1Biv
TS28: pulmonary artery Present 1Biv

Specimen 1Bv: embryonic day 15.5; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS23: pulmonary artery Present 1Bv

Specimen 1Bvi: postnatal day 2; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS27: pulmonary artery Present
TS27: lung vascular element Present 1Bvi As development proceeded, expression extended to capillaries.

Specimen 1Bvii: postnatal week 6; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS28: lung vascular element Present 1Bvii
TS28: pulmonary artery Present 1Bvii

Specimen 1Ci: postnatal day 2; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS27: blood vessel Present Regionally restricted 1Ci Expression was detected in blood vessels of the developing eye.
TS27: eye Present Regionally restricted 1Ci Expression was detected in blood vessels of the developing eye.

Specimen 1Cii: postnatal day 2; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS27: blood vessel Present Regionally restricted 1Cii Expression was detected in blood vessels of the developing spleen.
TS27: spleen Present Regionally restricted 1Cii Expression was detected in blood vessels of the developing spleen.

Specimen 1Ciii: postnatal day 2; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS27: blood vessel Present Regionally restricted 1Ciii Expression was detected in blood vessels of the developing thymus.
TS27: thymus Present Regionally restricted 1Ciii Expression was detected in blood vessels of the developing thymus.

Specimen 1Civ: postnatal day 2; Tmem100tm1Yjl/Tmem100+ (more )
Structure Level Pattern Image Note
TS27: blood vessel Present Regionally restricted 1Civ Expression was detected in blood vessels of the developing skin.
TS27: skin Present Regionally restricted 1Civ Expression was detected in blood vessels of the developing skin.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory