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Gene Expression Data
Assay Details
Assay
Reference: J:119301 Kadison SR, et al., The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord. Dev Biol. 2006 Aug 15;296(2):499-513
Assay type: RNA in situ
MGI Accession ID: MGI:6364840
Gene symbol: Slit3
Gene name: slit guidance ligand 3
Probe: Slit3 probe3
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 6I: embryonic day 12.5; Gli1tm1Alj/Gli1+, Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS20: spinal cord floor plate Strong 6I
TS20: spinal cord ventricular layer Present Regionally restricted 6I Expression in ventral ventricular zone.
TS20: spinal cord thoracic region Present Regionally restricted 6I Expression in motoneurons.
Specimen 6J: embryonic day 12.5; Gli1tm1Alj/Gli1tm1Alj (more )
Structure Level Pattern Image Note
TS20: spinal cord roof plate Present 6J
TS20: spinal cord ventricular layer Weak Regionally restricted 6J Expression in vicinity of the ventral ventricular zone, but a lower levels than that of Slit1.
TS20: spinal cord thoracic region Present Regionally restricted 6J Expression in motoneurons.
Specimen 6K: embryonic day 13.5; Gli1tm1Alj/Gli1+, Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS21: spinal cord Ambiguous 6K Expression significantly diminished in both heterozygous and homozygous mutants.
Specimen 6L: embryonic day 13.5; Gli1tm1Alj/Gli1tm1Alj (more )
Structure Level Pattern Image Note
TS21: spinal cord Ambiguous 6L Expression significantly diminished in both heterozygous and homozygous mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory