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Gene Expression Data
Assay Details
Assay
Reference: J:158147 Kinoshita M, et al., The novel protein kinase Vlk is essential for stromal function of mesenchymal cells. Development. 2009 Jun;136(12):2069-79
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6364615
Gene symbol: Pkdcc
Gene name: protein kinase domain containing, cytoplasmic
Reporter: GFP
Direct Detection
Results
Specimen 1A: embryonic day 6.5; Pkdcctm1.1Mask/Pkdcc+ (more )
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 1A Highest expression.
TS9: embryo Present Regionally restricted 1A Expressed in the gastrula organizer region.

Specimen 1C: embryonic day 7.5; Pkdcctm1.1Mask/Pkdcc+ (more )
Structure Level Pattern Image Note
TS11: anterior visceral endoderm Present 1C Highest expression.
TS11: node Present 1C

Specimen 1D: embryonic day 7.5; Pkdcctm1.1Mask/Pkdcc+ (more )
Structure Level Pattern Image Note
TS11: anterior visceral endoderm Present 1D Highest expression.
TS11: node Present 1D

Specimen 1F: embryonic day 9.5; Pkdcctm1.1Mask/Pkdcc+ (more )
Structure Level Pattern Image Note
TS15: pericardium Present 1F Expressed in the cardiac mesoderm.
TS15: branchial arch mesenchyme Present 1F Highest expression.
TS15: limb mesenchyme Present 1F Highest expression.
TS15: future midbrain Present Regionally restricted 1F Expressed in neuronal cells in the ventral part.

Specimen 1G: embryonic day 9.5; Pkdcctm1.1Mask/Pkdcc+ (more )
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present 1G Highest expression.

Specimen 1I: embryonic day 13.5; Pkdcctm1.1Mask/Pkdcc+ (more )
Structure Level Pattern Image Note
TS21: lung mesenchyme Present Widespread 1I Expressed in almost all cells.
TS21: pleura Present Widespread 1I Expressed in almost all cells.
TS21: bronchus mesenchyme Present Regionally restricted 1I Strongest expression in the peribronchial mesenchyme.
TS21: trachea mesenchyme Present Regionally restricted 1I Highest expression in the condensed mesenchymal cells lining the developing trachea.

Specimen 1J: postnatal day 0; Pkdcctm1.1Mask/Pkdcc+ (more )
Structure Level Pattern Image Note
TS27: pleura Present Regionally restricted 1J Expressed in the mesenchymal cells in the subpleural region and the pleural cells themselves.

Specimen 1N: embryonic day 12.5; Pkdcctm1.1Mask/Pkdcc+ (more )
Structure Level Pattern Image Note
TS20: humerus pre-cartilage condensation Strong 1N
TS20: radius-ulna pre-cartilage condensation Strong 1N
TS20: hand pre-cartilage condensation Absent 1N

Specimen 1O: embryonic day 13.5; Pkdcctm1.1Mask/Pkdcc+ (more )
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Present Regionally restricted 1O Expressed in proliferating chondrocytes and reserve chondrocytes.

Specimen 1P: embryonic day 14.5; Pkdcctm1.1Mask/Pkdcc+ (more )
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Strong Regionally restricted 1P Expressed in hypertrophic chondrocytes.

Specimen not shown: embryonic day 9.5; Pkdcctm1.1Mask/Pkdcc+ (more )
Note: Also stained for Cdh1 (assay MGI:6364877).
Structure Level Pattern Image Note
TS15: embryo mesenchyme Present
TS15: embryo ectoderm Present Regionally restricted Absent in most of the tissue. Only expressed in neuronal cells in the ventral part of the midbrain.
TS15: embryo endoderm Present Regionally restricted Not expressed in most of the endodermal cells, except for a small number of double-positive cells in the foregut.
TS15: foregut epithelium Present Regionally restricted Expressed in a small number of double-positive cells in the foregut.

Specimen not shown: postnatal; Pkdcctm1.1Mask/Pkdcc+ (more )
Structure Level Pattern Image Note
TS28: pleura Present Regionally restricted Expressed in mesothelial pleural cells throughout life.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory