Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:51693
Grimm C, et al., Aphakia (ak), a mouse mutation affecting early eye development: fine mapping, consideration of candidate genes and altered Pax6 and Six3 gene expression pattern. Dev Genet. 1998;23(4):299-316
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:6364194
|
|
Gene symbol:
|
Six3
|
|
Gene name:
|
sine oculis-related homeobox 3
|
|
Probe:
|
Six3 cDNA6
|
|
Probe preparation:
|
Antisense RNA
|
|
|
Results
|
Specimen
6A:
embryonic day 12.5
(more  )
Specimen
6A:
(close  )
|
Genetic Background:
|
either: C3H or (C3H x 102)F1
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
6B:
embryonic day 13.5
(more )
Specimen
6B:
(close )
|
Genetic Background:
|
either: C3H or (C3H x 102)F1
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
6C:
embryonic day 15.5
(more )
Specimen
6C:
(close )
|
Genetic Background:
|
either: C3H or (C3H x 102)F1
|
|
Age:
|
embryonic day 15.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
6D:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * C57BL/6 * C57BLKS
|
|
Mutant Allele(s):
|
Pitx3ak/Pitx3ak
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
6F:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * C57BL/6 * C57BLKS
|
|
Mutant Allele(s):
|
Pitx3ak/Pitx3ak
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
6E/G:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * C57BL/6 * C57BLKS
|
|
Mutant Allele(s):
|
Pitx3ak/Pitx3ak
|
|
Age:
|
embryonic day 15.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: neural retina |
Strong |
|
6E
,
6G
|
|
| TS23: lens |
Weak |
Regionally restricted |
6E
,
6G
|
No signal was detected in the corneal plug, which is probably part of the persisting lens stalk.
|
|
Analysis Tools