Gene Expression Data
Assay Details
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Assay
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Reference:
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J:118802
Blak AA, et al., Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. Dev Biol. 2007 Mar 1;303(1):231-43
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6363701
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Gene symbol:
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Slc6a4
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Gene name:
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solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
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Probe:
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Sert probe2
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Probe preparation:
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Antisense RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
3Ac:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Fgfr2tm1Wrst/Fgfr2tm1Wrst
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: midbrain |
Present |
Regionally restricted |
3Ac
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Expression in serotonergic neurons in dorsal raphe nuclei arising from rhombomere 1.
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Specimen
3Ac':
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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En1tm2(cre)Wrst/En1+
Fgfr2tm1Wrst/Fgfr2tm1Wrst
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: midbrain |
Present |
Regionally restricted |
3Ac'
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Expression unchanged compared to control.
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Specimen
3Bc:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Fgfr2tm1Wrst/Fgfr2tm1Wrst
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: midbrain |
Present |
Regionally restricted |
3Bc
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Expression in serotonergic neurons.
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Specimen
3Bc':
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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En1tm2(cre)Wrst/En1+
Fgfr2tm1Wrst/Fgfr2tm1Wrst
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: midbrain |
Present |
Regionally restricted |
3Bc'
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Expression unchanged compared to control.
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Specimen
4Bb:
postnatal adult
(more  )
Specimen
4Bb:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dorsal raphe nucleus |
Present |
Regionally restricted |
4Bb
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Expression in serotonergic neurons in dorsal raphe nucleus.
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Specimen
4Bb':
(close )
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Genetic Background:
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involves: 129S6/SvEvTac
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Mutant Allele(s):
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Fgfr3tm1Dor/Fgfr3tm1Dor
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Analysis Tools