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Gene Expression Data
Assay Details
Assay
Reference: J:118802 Blak AA, et al., Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. Dev Biol. 2007 Mar 1;303(1):231-43
Assay type: RNA in situ
MGI Accession ID: MGI:6363698
Gene symbol: Nkx2-2
Gene name: NK2 homeobox 2
Probe: Nkx2-2 probe10
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Results
Specimen 2Bb: embryonic day 12.5; Fgfr2tm1Wrst/Fgfr2tm1Wrst (more )
Structure Level Pattern Image Note
TS20: midbrain lateral wall Present Regionally restricted 2Bb Expression at alar/basal plate boundary.
TS20: midbrain ventricular layer Present Regionally restricted 2Bb Expression at in a small ventricular population in the alar plate.

Specimen 2Bb': embryonic day 12.5; En1tm2(cre)Wrst/En1+, Fgfr2tm1Wrst/Fgfr2tm1Wrst (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: midbrain lateral wall Present Regionally restricted 2Bb' Expression unchanged compared to control.
TS20: midbrain ventricular layer Present Regionally restricted 2Bb' Expression unchanged compared to control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory