About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:118802 Blak AA, et al., Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. Dev Biol. 2007 Mar 1;303(1):231-43
Assay type: RNA in situ
MGI Accession ID: MGI:6363686
Gene symbol: En1
Gene name: engrailed 1
Probe: En1 probe30
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Results
Specimen 2Aa: embryonic day 10.5; Fgfr2tm1Wrst/Fgfr2tm1Wrst (more )
Structure Level Pattern Image Note
TS17: hindbrain Present 2Aa Expression in presumptive midbrain-hindbrain region.
TS17: midbrain Present 2Aa Expression in presumptive midbrain-hindbrain region.
TS17: midbrain-hindbrain junction Present 2Aa Expression in presumptive midbrain-hindbrain region.
Specimen 2Aa': embryonic day 10.5; En1tm2(cre)Wrst/En1+, Fgfr2tm1Wrst/Fgfr2tm1Wrst (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: hindbrain Present 2Aa' Expression unchanged compared to control.
TS17: midbrain Present 2Aa' Expression unchanged compared to control.
TS17: midbrain-hindbrain junction Present 2Aa' Expression unchanged compared to control.
Specimen 2Ab: embryonic day 12.5; Fgfr2tm1Wrst/Fgfr2tm1Wrst (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 2Ab Expression marks posterior midbrain and rhombomere 1.
TS20: midbrain Present Regionally restricted 2Ab Expression marks posterior midbrain and rhombomere 1.
TS20: midbrain-hindbrain junction Present 2Ab
Specimen 2Ab': embryonic day 12.5; En1tm2(cre)Wrst/En1+, Fgfr2tm1Wrst/Fgfr2tm1Wrst (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 2Ab' Expression unchanged compared to control.
TS20: midbrain Present Regionally restricted 2Ab' Expression unchanged compared to control.
TS20: midbrain-hindbrain junction Present 2Ab' Expression unchanged compared to control.
Specimen 4Aa: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Present 4Aa Expression in presumptive midbrain-hindbrain region.
TS20: midbrain Present 4Aa Expression in presumptive midbrain-hindbrain region.
TS20: midbrain-hindbrain junction Present 4Aa Expression in presumptive midbrain-hindbrain region.
Specimen 4Aa': embryonic day 12.5; Fgfr3tm1Dor/Fgfr3tm1Dor (more )
Structure Level Pattern Image Note
TS20: hindbrain Present 4Aa' Expression unchanged compared to control.
TS20: midbrain Present 4Aa' Expression unchanged compared to control.
TS20: midbrain-hindbrain junction Present 4Aa' Expression unchanged compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory