Tg(Il15,-EGFP)20Pmr
Transgene Detail
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| Symbol: |
Tg(Il15,-EGFP)20Pmr |
| Name: |
transgene insertion 20, Philippa Marrack |
| MGI ID: |
MGI:6363417 |
| Synonyms: |
IL-15TE reporter |
| Transgene: |
Tg(Il15,-EGFP)20Pmr Location: unknown
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| Alliance: |
Tg(Il15,-EGFP)20Pmr page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Il15,-EGFP)20Pmr expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Il15 (MGI:103014) |
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Mutation details: BAC clone RP23-331F16, which included the entire IL-15 genomic locus was modified as follows: Sequences coding for 2A-peptide from Thosea asigna virus (TaV) RAEGRGSLLTCGDVEENPGP, and Enhanced Green Fluorescence Protein (EGFP), were inserted at the end of exon 8. This transgene expresses both mouse Il15 and EGFP with the self-cleaving 2A linker. Founder line 20 containing 2 copies of the transgene was selected for further analysis.
(J:193471)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:193471 Sosinowski T, et al., CD8alpha+ Dendritic Cell Trans Presentation of IL-15 to Naive CD8+ T Cells Produces Antigen-Inexperienced T Cells in the Periphery with Memory Phenotype and Function. J Immunol. 2013 Mar 1;190(5):1936-47 |
| All: |
3 reference(s) |
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Analysis Tools
