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Gene Expression Data
Assay Details
Assay
Reference: J:108723 Andersson O, et al., Synergistic interaction between Gdf1 and Nodal during anterior axis development. Dev Biol. 2006 May 15;293(2):370-81
Assay type: RNA in situ
MGI Accession ID: MGI:6363329
Gene symbol: Six3
Gene name: sine oculis-related homeobox 3
Probe: Six3 probe28
Probe preparation: labelled with digoxigenin
Results
Specimen 3E WT: embryonic day 9.0 (more )
Note: Also stained for Egr2 (assay MGI:6363330).
Structure Level Pattern Image Note
TS14: prosencephalon Present 3E WT Expression in forebrain.
Specimen 3E G-/- N+/-: embryonic day 9.0; Gdf1tm1Sjl/Gdf1tm1Sjl, Nodaltm1Rob/Nodal+ (more )
Note: Also stained for Egr2 (assay MGI:6363330).
Structure Level Pattern Image Note
TS14: prosencephalon Absent 3E G-/- N+/- Expression downregulated indicating anterior truncation of forebrain. Authors report expression was variably affected, ranging from no difference to complete loss in the most affected embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory