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Gene Expression Data
Assay Details
Assay
Reference: J:28289 Clark JC, et al., Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7794-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6363175
Gene symbol: Sftpb
Gene name: surfactant associated protein B
Antibody: anti-pro-SP-B
Results
Specimen 2 -/-: embryonic day 17.5; Sftpbtm1Jaw/Sftpbtm1Jaw (more )
Structure Level Pattern Image Note
TS25: bronchiole Absent 2_left
TS25: lung alveolus Absent 2_left
Specimen 2 WT: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lung alveolus Present Regionally restricted 2_right Expressed in type II cells.
TS25: bronchiole Present 2_right
Specimen not shown +/-: embryonic day 17.5; Sftpbtm1Jaw/Sftpb+ (more )
Structure Level Pattern Image Note
TS25: lung alveolus Present Regionally restricted Expressed in type II cells, same as in the wild-type.
TS25: bronchiole Present Same as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory