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Gene Expression Data
Assay Details
Assay
Reference: J:270176 Tian Z, et al., Deletion of epithelial cell-specific Cdc42 leads to enamel hypermaturation in a conditional knockout mouse model. Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2623-2632
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6363085
Gene symbol: Klk4
Gene name: kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)
Antibody: KLK4 antibody (orb13527)
Detection system: Secondary antibody
Assay notes: Fixative was 4% formaldehyde.
Results
Specimen 6E WT secretory: postnatal month 2; Cdc42tm1Yizh/? (more )
Note: Control animals (WT) were either homozygous Cdc42tm1Yizh/Cdc42tm1Yizh or heterozygous Cdc42tm1Yizh/+.
Structure Level Pattern Image Note
TS28: enamel organ Weak Regionally restricted 6E Secretory WT Expression is present during maturation stage (shown is secretory).

Specimen 6E KO secretory: postnatal month 2; Cdc42tm1Yizh/Cdc42tm1Yizh, Tg(KRT5-cre)1Xya/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: enamel organ Weak Regionally restricted 6E Secretory KO Expression is present during maturation stage (shown is secretory).

Specimen 6E WT maturation: postnatal month 2; Cdc42tm1Yizh/? (more )
Note: Control animals (WT) were either homozygous Cdc42tm1Yizh/Cdc42tm1Yizh or heterozygous Cdc42tm1Yizh/+.
Structure Level Pattern Image Note
TS28: enamel organ Present 6E Maturation WT

Specimen 6E KO maturation: postnatal month 2; Cdc42tm1Yizh/Cdc42tm1Yizh, Tg(KRT5-cre)1Xya/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: enamel organ Weak 6E Maturation KO


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory