Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(KRT5-TFRC/OVA)1Ita
Name:	transgene insertion 1, Sato Itami
MGI ID:	MGI:6363015
Synonyms:	K5-mOVA, K5.mOVA
Transgene:	Tg(KRT5-TFRC/OVA)1Ita  Location: unknown
Alliance:	Tg(KRT5-TFRC/OVA)1Ita page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(KRT5-TFRC/OVA)1Ita expresses 2 genes Transgene expresses: Organism Expressed Gene Homolog in Mouse Note chicken OVAL (396058) human TFRC (7037) Tfrc  (MGI:98822)   Tg(KRT5-TFRC/OVA)1Ita expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note human KRT5 (3852) Krt5  (MGI:96702)   Mutation details: The transgene encodes a fusion protein comprising the carboxy-terminal 118 amino acids of the human transferrin receptor, which include the cytoplasmic tail, membrane-targeting signal and anchor domain of the protein, joined to amino acids 139-385 of mature ovalbumin. Its expression is directed by the human keratin 5 promoter. (J:131888)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:131888 Azukizawa H, et al., Induction of T-cell-mediated skin disease specific for antigen transgenically expressed in keratinocytes. Eur J Immunol. 2003 Jul;33(7):1879-88
All:	11 reference(s)