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Gene Expression Data
Assay Details
Assay
Reference: J:215297 Voronov D, et al., Transcription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration. Invest Ophthalmol Vis Sci. 2013 May;54(5):3115-25
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6361768
Gene symbol: Runx1
Gene name: runt related transcription factor 1
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 17.5; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS25: lacrimal gland epithelium Present 2A
TS25: parotid gland epithelium Present 2A

Specimen 2B: embryonic day 17.5; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS25: lacrimal gland epithelium Present 2B

Specimen 2C: embryonic day 17.5; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS25: sublingual gland epithelium Present 2C
TS25: submandibular gland epithelium Present 2C

Specimen 2D: postnatal month 6; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS28: meibomian gland Present Regionally restricted 2D Expressed in ductal and mesenchymal components.
TS28: eyelash Present Regionally restricted 2D Expressed in the follicle bulge region.

Specimen 2E: postnatal month 6; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS28: meibomian gland Present Regionally restricted 2E Expressed in ductal and mesenchymal components.
TS28: eyelash Present Regionally restricted 2E Expressed in the follicle bulge region.

Specimen 2F: embryonic day 12.5; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS20: lung epithelium Present 2F

Specimen 2G: postnatal day 0; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS27: lacrimal gland epithelium Strong Regionally restricted 2G Expressed in ductal epithelium in a subset of cells within the acini called centroacinar cells.

Specimen 2H: postnatal day 0; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS27: lacrimal gland epithelium Strong Regionally restricted 2H Expressed in ductal epithelium in a subset of cells within the acini called centroacinar cells.

Specimen 2I: postnatal day 17; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS28: lacrimal gland epithelium Strong Regionally restricted 2I Expressed in ductal epithelium in a subset of cells within the acini called centroacinar cells.

Specimen 2J: postnatal day 17; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS28: lacrimal gland epithelium Strong Regionally restricted 2J Expressed in ductal epithelium in a subset of cells within the acini called centroacinar cells.

Specimen 2K: postnatal month 6; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS28: lacrimal gland epithelium Strong Regionally restricted 2K Expressed in ductal epithelium in a subset of cells within the acini called centroacinar cells.

Specimen 2L: postnatal month 6; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS28: lacrimal gland epithelium Strong Regionally restricted 2L Expressed in ductal epithelium in a subset of cells within the acini called centroacinar cells.

Specimen 2M: postnatal month 6; Runx1tm1Medv/Runx1+ (more )
Note: Also stained by PAS.
Structure Level Pattern Image Note
TS28: lacrimal gland epithelium Present Regionally restricted 2M Expressed in all PAS+ ducts and centroacinar cells and some PAS- acinar cells.

Specimen 2N: postnatal month 6; Runx1tm1Medv/Runx1+ (more )
Note: Also stained by PAS.
Structure Level Pattern Image Note
TS28: lacrimal gland epithelium Present Regionally restricted 2N Expressed in all PAS+ ducts and centroacinar cells and some PAS- acinar cells.

Specimen 2O: postnatal month 6; Runx1tm1Medv/Runx1+ (more )
Note: Also stained by PAS.
Structure Level Pattern Image Note
TS28: lacrimal gland epithelium Present Regionally restricted 2O Expressed in all PAS+ ducts and centroacinar cells and some PAS- acinar cells.

Specimen not shown: postnatal month 6; Runx1tm1Medv/Runx1+ (more )
Structure Level Pattern Image Note
TS28: parotid gland myoepithelium Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory