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Gene Expression Data
Assay Details
Assay
Reference: J:74155 Kagoshima M, et al., Diverse gene expression and function of semaphorins in developing lung: positive and negative regulatory roles of semaphorins in lung branching morphogenesis. Genes Cells. 2001 Jun;6(6):559-71
Assay type: RNA in situ
MGI Accession ID: MGI:6361501
Gene symbol: Plxna1
Gene name: plexin A1
Probe: Plex-A1 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1P: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lobar bronchus epithelium Present Regionally restricted 1P Expression in epithelial cells lining luminal side of bronchi.
TS19: lobar bronchus mesenchyme Present 1P
Specimen 1Q: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lobar bronchus epithelium Present Regionally restricted 1Q Continuous expression in epithelium of lobar bronchus.
TS21: lobar bronchus mesenchyme Present 1Q Expression in mesenchyme surrounding lobar bronchi, gradually decreasing from E11.5 to E17.5.
Specimen 1R: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lobar bronchus epithelium Present Regionally restricted 1R Continuous expression in epithelium of lobar bronchus.
TS21: lobar bronchus mesenchyme Present 1R Expression in mesenchyme surrounding lobar bronchi, gradually decreasing from E11.5 to E17.5.
Specimen 2K: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lobar bronchus mesenchyme Present 2K Expression in mesenchyme surrounding lobar bronchi, gradually decreasing from E11.5 to E17.5.
TS23: lung epithelium Strong Regionally restricted 2K High expression localized mainly in terminal buds.
Specimen 2L: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lobar bronchus mesenchyme Present 2L Expression in mesenchyme surrounding lobar bronchi, gradually decreasing from E11.5 to E17.5.
TS23: lung epithelium Strong Regionally restricted 2L High expression localized mainly in terminal buds.
Specimen 3K: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lobar bronchus mesenchyme Weak 3K Expression in mesenchyme surrounding lobar bronchi, gradually decreasing from E11.5 to E17.5.
TS25: lobar bronchus epithelium Present 3K
TS25: bronchiole Present 3K
Specimen 3L: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lobar bronchus mesenchyme Weak 3L Expression in mesenchyme surrounding lobar bronchi, gradually decreasing from E11.5 to E17.5.
TS25: bronchiole Present 3L
TS25: lobar bronchus epithelium Present 3L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory