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Gene Expression Data
Assay Details
Assay
Reference: J:74155 Kagoshima M, et al., Diverse gene expression and function of semaphorins in developing lung: positive and negative regulatory roles of semaphorins in lung branching morphogenesis. Genes Cells. 2001 Jun;6(6):559-71
Assay type: RNA in situ
MGI Accession ID: MGI:6361499
Gene symbol: Nrp1
Gene name: neuropilin 1
Probe: NP-1 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lung mesenchyme Strong Regionally restricted 1J Intense expression in mesenchyme surrounding epithelial tubules.
TS19: lung vascular element Strong Regionally restricted 1J Intense expression in mesenchyme surrounding epithelial tubules.

Specimen 1K: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung mesenchyme Strong Regionally restricted 1K Intense expression in mesenchyme surrounding epithelial tubules.
TS21: lung vascular element Strong 1K High levels of expression in blood vessels of lung.
TS21: heart Strong 1K

Specimen 1L: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung mesenchyme Strong Regionally restricted 1L Intense expression in mesenchyme surrounding epithelial tubules.
TS21: lung vascular element Strong 1L High levels of expression in blood vessels of lung.

Specimen 2G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lung mesenchyme Strong Regionally restricted 2G Intense expression in mesenchyme surrounding epithelial tubules.
TS23: lung epithelium Strong Regionally restricted 2G Strong expression in luminal side of epithelial tubules of terminal buds.
TS23: lung vascular element Strong 2G
TS23: heart Strong 2G

Specimen 2H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lung mesenchyme Strong Regionally restricted 2H Intense expression in mesenchyme surrounding epithelial tubules.
TS23: lung epithelium Strong Regionally restricted 2H Strong expression in luminal side of epithelial tubules of terminal buds.
TS23: lung vascular element Strong 2H Intense expression in blood vessels, mainly in larger pulmonary blood vessels.

Specimen 3G: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lung mesenchyme Strong Regionally restricted 3G Intense expression in mesenchyme surrounding epithelial tubules.
TS25: lung epithelium Strong Regionally restricted 3G Strong expression in luminal side of epithelial tubules of terminal buds.
TS25: lung vascular element Strong 3G

Specimen 3H: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lung mesenchyme Strong Regionally restricted 3H Intense expression in mesenchyme surrounding epithelial tubules.
TS25: terminal bronchiole Strong Regionally restricted 3H Strong expression in luminal side of epithelial tubules of terminal buds.
TS25: lung vascular element Strong Regionally restricted 3H Intense expression in blood vessels, mainly in larger pulmonary blood vessels.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory