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Gene Expression Data
Assay Details
Assay
Reference: J:74155 Kagoshima M, et al., Diverse gene expression and function of semaphorins in developing lung: positive and negative regulatory roles of semaphorins in lung branching morphogenesis. Genes Cells. 2001 Jun;6(6):559-71
Assay type: RNA in situ
MGI Accession ID: MGI:6361497
Gene symbol: Sema3c
Gene name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Probe: Sema3C probe8
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lobar bronchus epithelium Strong 1D High expression almost restricted to epithelium of lobar bronchi.
TS19: lung mesenchyme Ambiguous 1D Little or no expression in mesenchyme.
Specimen 1E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lobar bronchus epithelium Strong 1E High expression almost restricted to epithelium of lobar bronchi.
TS21: lung mesenchyme Ambiguous 1E Little or no expression in mesenchyme.
Specimen 1F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lobar bronchus epithelium Strong 1F High expression almost restricted to epithelium of lobar bronchi.
TS21: lung mesenchyme Ambiguous 1F Little or no expression in mesenchyme.
Specimen 2C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lobar bronchus Present 2C Expression mainly in lobar bronchus.
TS23: bronchiole Weak 2C Lower expression in bronchioles.
Specimen 2D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lobar bronchus Present 2D Expression mainly in lobar bronchus.
TS23: bronchiole Weak 2D Lower expression in bronchioles.
Specimen 3C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lobar bronchus Present 3C Expression restricted to lobar bronchus.
Specimen 3D: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lobar bronchus Present 3D Expression restricted to lobar bronchus.
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lobar bronchus Weak Expression in lobar bronchus right through to adult, although expression was down-regulated at later stages.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory