Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tekem1(dre)Bzsh
Name:	TEK receptor tyrosine kinase; endonuclease-mediated mutation 1, Bin Zhou
MGI ID:	MGI:6361468
Synonyms:	Tie2-Dre
Gene:	Tek  Location: Chr4:94627526-94763213 bp, + strand  Genetic Position: Chr4, 43.34 cM
Alliance:	Tekem1(dre)Bzsh page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Tekem1(dre)Bzsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tek (MGI:98664)   Mutation details: The mouse line was generated by homologous recombination using the CRISPR/Cas9 technology. A cDNA encoding Dre recombinase, followed by a polyadenylation sequence, was inserted into the translation start site of the Tek gene. (J:236001)

Activity:	Tissue activity of this recombinase allele
Driver:	Tek (mouse) Summary of all recombinase alleles driven by Tek. Comparative matrix view of recombinase activities Alliance mouse Tek gene page

In Mice Carrying this Mutation:

80 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tek Mutation:	92 strains or lines available

Original:	J:236001 Zhang H, et al., Endocardium Contributes to Cardiac Fat. Circ Res. 2016 Jan 22;118(2):254-65
All:	3 reference(s)