About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:108393 Chung AC, et al., Loss of orphan nuclear receptor GCNF function disrupts forebrain development and the establishment of the isthmic organizer. Dev Biol. 2006 May 1;293(1):13-24
Assay type: RNA in situ
MGI Accession ID: MGI:6360873
Gene symbol: Nr6a1
Gene name: nuclear receptor subfamily 6, group A, member 1
Probe: Gcnf cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 8.0 (more )
Note: 3 somites
Structure Level Pattern Image Note
TS12: neural ectoderm Present Graded 1A Expression in proliferating neuroepithelium, with a gradient from posterior to anterior ends.
Specimen 1B: embryonic day 8.5 (more )
Note: 6 somites
Structure Level Pattern Image Note
TS12: future brain Present 1B Expression in anterior neuroepithelium.
Specimen 1C: embryonic day 8.75 (more )
Note: 13 somites
Structure Level Pattern Image Note
TS14: future brain Weak 1C Expression decreased in anterior when somite number was greater than 12.
Specimen 1D: embryonic day 9.5 (more )
Note: 25 somites
Structure Level Pattern Image Note
TS15: future forebrain Trace 1D Expression markedly reduced in forebrain and midbrain regions.
TS15: future midbrain Trace 1D Expression markedly reduced in forebrain and midbrain regions.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory