Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Amelx-icre)854Ppap
Name:	transgene insertion 854, Petros Papagerakis
MGI ID:	MGI:6360644
Synonyms:	Amelx-iCre(854)
Transgene:	Tg(Amelx-icre)854Ppap  Location: unknown
Alliance:	Tg(Amelx-icre)854Ppap page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Amelx-icre)854Ppap expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Amelx (MGI:88005)   Mutation details: The transgene was created by modifying BAC by replacing exon 2 of mouse Amelx gene with an improved cre recombinase gene (icre). An FRT-flanked kanomycin resistance cassette was removed prior to injection. 4 independent BAC founder lines (854, 863, 872, and 876) were collected. Line 854 showed the X-gal staining in ameloblasts and very light staining activity in the bone tissue. (J:278625)

Activity:	Tissue activity of this recombinase allele
Driver:	Amelx (mouse) Summary of all recombinase alleles driven by Amelx. Comparative matrix view of recombinase activities Alliance mouse Amelx gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:278625 Said R, et al., Generation of Amelx-iCre Mice Supports Ameloblast-Specific Role for Stim1. J Dent Res. 2019 Aug;98(9):1002-1010
All:	1 reference(s)