Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Slc6a4tm1.1(flpo)Luo
Name:	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; targeted mutation 1.1, Liqun Luo
MGI ID:	MGI:6360133
Gene:	Slc6a4  Location: Chr11:76889429-76923166 bp, + strand  Genetic Position: Chr11, 46.18 cM
Alliance:	Slc6a4tm1.1(flpo)Luo page

Germline Transmission:	Earliest citation of germline transmission: J:101977
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac x C57BL/6J

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Slc6a4tm1.1(flpo)Luo expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Slc6a4 (MGI:96285)   Mutation details: An IRES-FlpO-loxP2272-ACE-Cre POII NeoR-loxp2272 cassette was inserted after the TAA stop codon of Slc6a4/Sert via homologous recombination in embryonic stem (ES) cells. The loxP2272-ACE-Cre POII NeoR-loxp2272 portion of the mutation is self-excised. (J:101977)

Activity:	Tissue activity of this recombinase allele
Driver:	Slc6a4 (mouse) Summary of all recombinase alleles driven by Slc6a4. Alliance mouse Slc6a4 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc6a4 Mutation:	51 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	3 reference(s)